Carbonic Anhydrase 7 (CA7) is a member of the alpha-carbonic anhydrase family. Alpha-carbonic anhydrase is a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. Furthermore; Alpha-carbonic anhydrase is associated with many biological processes; including calcification; respiration; bone resorption; acid-base balance and the formation of aqueous humor. CA7 is activated by histamine; L-adrenaline; L- and D-histidine; and L- and D-phenylalanine; but it is inhibited coumarins; sulfonamide derivatives such as acetazolamide (AZA) by saccharin and Foscarnet.
Product Name:
Carbonic Anhydrase 7/CA7 Recombinant Protein (RPES4302)
Measured by its esterase activity The specific activity is 2862 pmol/min/ug .
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Human Carbonic Anhydrase 7 is produced by our E.coli expression system and the target gene encoding Met1-Ala264 is expressed with a 6His tag at the C-terminus.
Purity:
> 95 % as determined by reducing SDS-PAGE.
Mol Mass:
30.7 kDa
AP Mol Mass:
31 kDa
Formulation:
Supplied as a 0.2 µm filtered solution of 20mM TrisHCl; 150mM NaCl; pH 8.0 .
Shipping:
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt; store it immediately at<-20°C.
Stability and Storage:
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
