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Human CD300a/LMIR1 Recombinant Protein (RPES3464)

SKU:
RPES3464
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Cell Biology
$265
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Description

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Human CD300a/LMIR1 Recombinant Protein

CD300A is a single-pass type I membrane protein that belongs to the CD300 family. CD300A consists of a 163 amino acid (aa) extracellular domain (ECD) with one Ig-like V- type domain; a 21 amino acid transmembrane segment; and a 98 amino acid cytoplasmic domain with tyrosine residues. CD300A is expressed not only by natural killer (NK) cells but also by T-cell subsets; B-cells; dendritic cells; mast cells; granulocytes and monocytes. CD300A is an inhibitory receptor which may contribute to the down-regulation of cytolytic activity in natural killer (NK) cells; and to the down-regulation of mast cell degranulation.