There are numerous D-amino acids that act as substrates, with the exception of naturally occurring L-amino acids. The biological function of D-amino-acid oxidase/DAO is unknown; it may act as a detoxifying agent by removing D-enzyme from cells during aging. DAO degrades D-serine, which is a co-agonist of the NMDA receptor, in mice. D-amino-acid oxidase/DAO may be linked to schizophrenia. Bipolar disorder and amyotrophic lateral sclerosis 1 are examples of diseases linked to DAO. Glycine degradation, glyoxylate metabolism, along with viral mRNA translation are among the pathways influenced by D-amino-acid oxidase/DAO.D-Amino-Acid Oxidase/DAO Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.
Product Name:
D-Amino-Acid Oxidase/DAO Recombinant Protein (RPES2081)
Product Code:
RPES2081
Size:
10µg
Species:
Human
Expressed Host:
E.coli
Synonyms:
D-Amino-Acid Oxidase, DAAO, DAMOX, DAO
Accession:
P14920
Sequence:
Met 1-Leu347
Fusion tag:
N-6His
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Human D-Amino-Acid Oxidase is produced by our E.coli expression system and the target gene encoding Met1-Leu347 is expressed with a 6His tag at the N-terminus.
Purity:
> 90 % as determined by reducing SDS-PAGE.
Mol Mass:
41.6 kDa
AP Mol Mass:
40 kDa
Formulation:
Supplied as a 0.2 µm filtered solution of 20mM TrisHCl, 150mM NaCl, 1mM DTT, 2mM EDTA, pH 8.0 .
Shipping:
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C.
Stability and Storage:
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
