Activin and inhibin are two protein complexes that have nearly opposite biological effects. TGF-β superfamily members, activins, are disulfide-linked dimeric proteins that were originally isolated from gonadal fluids as proteins that stimulated pituitary FSH release. Depending on the subunit composition, inhibins/activins are involved in regulating a variety of functions including hypothalamic and pituitary hormone production, gonadal hormone synthesis, germ cell development and maturation, erythroid differentiation, insulin manufacture, nerve survival, embryonic axial growth or bone growth. Actins are heterodimers or homodimers of the various beta subunit versions, while inhibins are heterodimeric combinations of a distinct alpha subunit and one of the many beta subunits. Activin A/INHBA Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.
Activin A/INHBA Recombinant Protein (RPES0228)
Inhibin beta A chain,INHBA,Activin A
<1.0 EU per µg as determined by the LAL method.
Recombinant Human/Mouse/Rat Activin A is produced by our Mammalian expression system and the target gene encoding Gly311-Ser426 is expressed.
> 95% as determined by reducing SDS-PAGE.
AP Mol Mass:
Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.