Human NACHRA5/CHRNA5 Recombinant Protein (RPES0832)
- SKU:
- RPES0832
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Signal Transduction
Frequently bought together:
Description
system_update_altDatasheet
Human NACHRA5/CHRNA5 Recombinant Protein
Neuronal Acetylcholine Receptor Subunit ?-5 (NACHRA5) is a member of the ligand-gated ion channel family. Neuronal AChR is composed of two different type of subunits: ? and non-?. When NACHRA5 binds to acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits, leading to the opening of an ion-conducting channel across the plasma membrane. Genetic variations in NACHRA5 have been related to susceptibility to smoking-related behavioral traits and lung cancer, contributing to the smoking quantitative trait locus 3.
| Product Name: | Human NACHRA5/CHRNA5 Recombinant Protein (RPES0832) |
| Product Code: | RPES0832 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | Human Cells |
| Synonyms: | Neuronal Acetylcholine Receptor Subunit Alpha-5, CHRNA5, NACHRA5 |
| Accession: | P30532 |
| Sequence: | Arg23-Thr254 |
| Fusion tag: | C-His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human NACHRA5 is produced by our Mammalian expression system and the target gene encoding Arg23-Thr254 is expressed with a 6His tag at the C-terminus. |
| Purity: | > 90% as determined by reducing SDS-PAGE. |
| Mol Mass: | 27.6 kDa |
| AP Mol Mass: | 35-40 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
