The NDRG1 gene is a member of the alpha/beta hydrolase family and part of the N-myc downregulated gene family. NDRG1 is a cytoplasmic protein that is involved in stress, hormone responses, cellular growth, and development. The protein NDRG1 is involved in p53-induced caspase activation and cell death. Charcot-Marie-Tooth disease type 4D is caused by defects in NDRG1, and the expression of NDRG1 may be a predictor for various types of cancer. C-MYC transcriptional repression and Direct p53 effectors are two pathways connected to NDRG1. Human NDRG1 Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.
Human NDRG1 Recombinant Protein (RPES0646)
Protein NDRG1, Differentiation-Related Gene 1 Protein, DRG-1, N-myc Downstream-Regulated Gene 1 Protein, Nickel-Specific Induction Protein Cap43, Reducing Agents and Tunicamycin-Responsive Protein, RTP, Rit42, NDRG1, CAP43, DRG1, RTP
<1.0 EU per µg as determined by the LAL method.
Recombinant Human N-myc Downstream Regulated Gene 1 is produced by our E.coli expression system and the target gene encoding Met1-Cys394 is expressed with a 6His tag at the N-terminus.
> 90 % as determined by reducing SDS-PAGE.
AP Mol Mass:
Lyophilized from a 0.2 µm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.