Description
| Product Name: | Recombinant Human PFN1 Protein (Sumo Tag) |
| SKU: | RPES8030 |
| Size: | 20μg |
| Tag: | N-Sumo |
| Reactivity: | Human |
| Expression Host: | E.coli |
| Accession: | P07737 |
| Sequence: | Met1-Tyr140 |
| Calculated Molecular Weight: | 28.3 kDa |
| Observed Molecular Weight: | 32 kDa |
| Synonyms: | Actin binding protein, ALS18, Epididymis tissue protein Li 184a, OTTHUMP00000125244, PFN 1, Pfn, PFN1, PROF1, Profilin I, Profilin-1, Profilin1, ProfilinI |
| Endotoxin: | < 10 EU/mg of the protein as determined by the LAL method |
| Purity: | > 90% as determined by reducing SDS-PAGE. |
This gene encodes a member of the profilin family of small actin-binding proteins. The encoded protein plays an important role in actin dynamics by regulating actin polymerization in response to extracellular signals. Deletion of this gene is associated with an Miller-Dieker syndrome, and the encoded protein may also play a role in Huntington disease. Multiple pseudogenes of this gene are located on chromosome 1.
| Bio-activity: | Not validated for activity |
| Formulation: | Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol. |
| Reconstitution: | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis. |
| Storage: | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
