Description
| Product Name: | Recombinant Human PODXL Protein (Fc Tag) |
| SKU: | RPES8265 |
| Size: | 20μg |
| Tag: | C-Fc |
| Reactivity: | Human |
| Expression Host: | Mammalian |
| Accession: | O00592 |
| Sequence: | Ser23-Pro461 |
| Calculated Molecular Weight: | 73.2 kDa |
| Observed Molecular Weight: | 90-100 kDa |
| Synonyms: | GCTM-2 antigen, Gp2, Gp200, MGC138240, PC, PCLP, PCLP-1, PCLP1, Pcx, Podocalyxin, Podocalyxin like, Podocalyxin like protein, Podocalyxin-like protein 1, Podxl, PODXL |
| Endotoxin: | < 1.0 EU/mg of the protein as determined by the LAL method |
| Purity: | > 90% as determined by reducing SDS-PAGE. |
This gene encodes a member of the sialomucin protein family. The encoded protein was originally identified as an important component of glomerular podocytes. Podocytes are highly differentiated epithelial cells with interdigitating foot processes covering the outer aspect of the glomerular basement membrane. Other biological activities of the encoded protein include: binding in a membrane protein complex with Na+/H+ exchanger regulatory factor to intracellular cytoskeletal elements, playing a role in hematopoetic cell differentiation, and being expressed in vascular endothelium cells and binding to L-selectin.
| Bio-activity: | Not validated for activity |
| Formulation: | Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol. |
| Reconstitution: | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis. |
| Storage: | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
