null

Human TRAIL R3/TNFRSF10C Recombinant Protein (RPES1041)

SKU:
RPES1041
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Cell Death
€132
Frequently bought together:

Description

system_update_altDatasheet

Human TRAIL R3/TNFRSF10C Recombinant Protein

Tumor Necrosis Factor Receptor Superfamily Member 10C (TNFRSF10C) is a glycosyl-phosphatidylinositol-linked membrane protein which binds TRAIL with high affinity. TNFRSF10C has the TRAIL-binding extracellular cysteine-rich domains; lacks the intracellular signaling domain. As a result; binding of TRAIL to TRAIL R3 doesnÂ’t transduce an apoptosis signal. The expression of TRAIL R3 gene has been shown to protect cells bearing TRAIL R1 and/or TRAIL R2 from TRAIL-induced apoptosis.