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Anti-SLC18A3 Antibody (CAB16067)

SKU:
CAB16067
Product Type:
Antibody
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Neuroscience
€129 - €359
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Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-SLC18A3 Antibody
Antibody SKU:CAB16067
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human SLC18A3 (NP_003046.2).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Rat
Positive Samples:
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human SLC18A3 (NP_003046.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MESA EPAG QARA AATK LSEA VGAA LQEP RRQR RLVL VIVC VALL LDNM LYMV IVPI VPDY IAHM RGGG EGPT RTPE VWEP TLPL PTPA NASA YTAN TSAS PTAA WPAG SALR PRYP TESE DVKI GVLF ASKA ILQL LVNP LSGP FIDR MS
Gene ID:6572
Uniprot:Q16572
Cellular Location:Membrane, Multi-pass membrane protein
Calculated MW:56kDa
Observed MW:Refer to figures
Synonyms:SLC18A3, CMS21, VACHT
Background:This gene is a member of the vesicular amine transporter family. The encoded transmembrane protein transports acetylcholine into secretory vesicles for release into the extracellular space. Acetylcholine transport utilizes a proton gradient established by a vacuolar ATPase. This gene is located within the first intron of the choline acetyltransferase gene.
UniProt Protein Function:SLC18A3: Involved in acetylcholine transport into synaptic vesicles. Belongs to the major facilitator superfamily. Vesicular transporter family.
UniProt Protein Details:

Protein type:Transporter; Transporter, SLC family; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 10q11.2

Cellular Component: membrane; integral to plasma membrane; plasma membrane

Molecular Function:acetylcholine transmembrane transporter activity

Biological Process: synaptic transmission; acetylcholine transport; neurotransmitter secretion

NCBI Summary:This gene is a member of the vesicular amine transporter family. The encoded transmembrane protein transports acetylcholine into secretory vesicles for release into the extracellular space. Acetylcholine transport utilizes a proton gradient established by a vacuolar ATPase. This gene is located within the first intron of the choline acetyltransferase gene. [provided by RefSeq, Jul 2008]
UniProt Code:Q16572
NCBI GenInfo Identifier:118582257
NCBI Gene ID:6572
NCBI Accession:NP_003046.2
UniProt Secondary Accession:Q16572,B2R7S1,
UniProt Related Accession:Q16572
Molecular Weight:56,903 Da
NCBI Full Name:vesicular acetylcholine transporter
NCBI Synonym Full Names:solute carrier family 18 (vesicular acetylcholine transporter), member 3
NCBI Official Symbol:SLC18A3  
NCBI Official Synonym Symbols:VACHT  
NCBI Protein Information:vesicular acetylcholine transporter
UniProt Protein Name:Vesicular acetylcholine transporter
UniProt Synonym Protein Names:Solute carrier family 18 member 3
Protein Family:Vesicular acetylcholine transporter
UniProt Gene Name:SLC18A3  
UniProt Entry Name:VACHT_HUMAN

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