The SPR Antibody (CAB11694) is a high-quality antibody developed for reliable detection and analysis of target proteins. This polyclonal antibody, generated in rabbits, has been rigorously validated for use in Western blotting applications and exhibits high reactivity with human samples.SPR, also known as steroid receptor RNA activator, plays a critical role in mediating cellular responses to environmental stimuli, hormonal signaling, and stress. Its involvement in immune regulation and disease pathogenesis makes it an attractive target for investigation in fields such as immunology, cancer research, and drug development.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
SPR Antibody
SKU:
CAB11694
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
SDR38C1, SPR
Positive Sample:
BxPC-3, Jurkat
Cellular Localization:
Cytoplasm.
Calculated MW:
28kDa
Observed MW:
31kDa
This gene encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on chromosome 1.
Purification Method
Affinity purification
Gene ID
6697
RRID
AB_2758693
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SPR Rabbit pAb (CAB11694) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 3s.
