The TBL1Y Monoclonal Antibody (MACO0363) is a valuable tool for researchers studying the TBL1Y protein, which is involved in chromatin remodeling and gene regulation. This antibody, generated in mice, is highly specific for TBL1Y and is suitable for use in various applications such as Western blotting, immunofluorescence, and immunoprecipitation.TBL1Y, a member of the WD40 repeat protein family, is known to interact with transcriptional corepressors and coactivators to regulate gene expression. Its role in chromatin remodeling and transcriptional regulation makes it a key player in various biological processes, including development, differentiation, and disease.
By using the TBL1Y Monoclonal Antibody (MACO0363), researchers can gain insights into the function and regulation of TBL1Y in different cell types and experimental conditions. This antibody is a valuable tool for investigating the molecular mechanisms underlying gene expression and chromatin organization, making it an essential component of research in the fields of epigenetics, developmental biology, and cancer biology.
Product Name:
Anti-TBL1Y Antibody
Product Sku:
MACO0363
Size:
100ul
Host Species:
Mouse
Tested Applications:
ELISA, WB, ICC
Recommended Dilutions:
WB:1:500-1:5000, ICC:1:50-1:200
Species Reactivity:
Human, Mouse, Pig, Rat, Dog
Immunogen:
Recombinant full length protein (522aa) of human TBL1Y.
Form:
Liquid
Storage Buffer:
Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol
Purification Method:
Antigen Affinity Purified
Clonality:
Monoclonal
Isotype:
IgG2b
Conjugate:
Non-conjugated
Background:
Synonyms:
F-box-like/WD repeat-containing protein TBL1Y transducin beta-like 1 transducin beta-like protein 1Y transducin-beta-like protein 1, Y-linked
UniProt Protein Function:
UniProt Protein Details:
NCBI Summary:
The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation. This gene is highly similar to TBL1X gene in nucleotide sequence and protein sequence, but the TBL1X gene is located on chromosome X and this gene is on chromosome Y. This gene has three alternatively spliced transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
