The TRPM8 Monoclonal Antibody (CAB4269) is a high-quality antibody developed for reliable detection and analysis of target proteins. TRPM8 is known as the cold and menthol receptor, playing a key role in detecting cold temperatures and sensations of cooling and menthol.This antibody, generated in rabbits, exhibits high specificity and sensitivity in detecting TRPM8 in human samples. Validated for use in Western blot applications, this antibody facilitates the identification and analysis of TRPM8 expression in various cell types. Its reliability and precision make it an ideal choice for research in areas such as sensory physiology, thermoregulation, and pain perception.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human samples.
Product Name:
TRPM8 Monoclonal Antibody
SKU:
CAB4269
Size:
20μL, 100μL
Reactivity:
Human
Clone Number:
ARC0947
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Predicted to enable ligand-gated calcium channel activity. Predicted to be involved in calcium ion transmembrane transport and positive regulation of cold-induced thermogenesis. Predicted to act upstream of or within several processes, including cellular calcium ion homeostasis; response to cold; and thermoception. Located in plasma membrane.
Purification Method
Affinity purification
Gene ID
79054
RRID
AB_2863221
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using TRPM8 Rabbit mAb (CAB4269) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 3min.
