UBA7 Antibody (PACO01671)
- SKU:
- PACO01671
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| Antibody Name: | UBA7 Antibody |
| Antibody SKU: | PACO01671 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | WB:1:500-1:2000, IHC:1:100-1:300 |
| Species Reactivity: | Human |
| Immunogen: | synthesized peptide derived from the C-terminal region of human UBE1L. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | UBA7; UBE1L; UBE2; Ubiquitin-like modifier-activating enzyme 7; Ubiquitin-activating enzyme 7; D8; Ubiquitin-activating enzyme E1 homolog |
| UniProt Protein Function: | UBE1L: Activates ubiquitin by first adenylating with ATP its C- terminal glycine residue and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding an ubiquitin- E1 thioester and free AMP. Belongs to the ubiquitin-activating E1 family. |
| UniProt Protein Details: | Protein type:Ubiquitin conjugating system; Ubiquitin ligase; EC 6.3.2.19 Chromosomal Location of Human Ortholog: 3p21 Cellular Component: cytosol; nucleoplasm; nucleus Molecular Function:ISG15 activating enzyme activity; protein binding; ubiquitin activating enzyme activity; ubiquitin-protein ligase activity Biological Process: bypass DNA synthesis; ISG15-protein conjugation; modification-dependent protein catabolic process; negative regulation of interferon type I production; protein modification process |
| NCBI Summary: | The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme is a retinoid target that triggers promyelocytic leukemia (PML)/retinoic acid receptor alpha (RARalpha) degradation and apoptosis in acute promyelocytic leukemia, where it is involved in the conjugation of the ubiquitin-like interferon-stimulated gene 15 protein. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P41226 |
| NCBI GenInfo Identifier: | 215273977 |
| NCBI Gene ID: | 7318 |
| NCBI Accession: | P41226.2 |
| UniProt Secondary Accession: | P41226,Q9BRB2, |
| UniProt Related Accession: | P41226 |
| Molecular Weight: | 111,694 Da |
| NCBI Full Name: | Ubiquitin-like modifier-activating enzyme 7 |
| NCBI Synonym Full Names: | ubiquitin like modifier activating enzyme 7 |
| NCBI Official Symbol: | UBA7 |
| NCBI Official Synonym Symbols: | D8; UBE2; UBA1B; UBE1L |
| NCBI Protein Information: | ubiquitin-like modifier-activating enzyme 7 |
| UniProt Protein Name: | Ubiquitin-like modifier-activating enzyme 7 |
| UniProt Synonym Protein Names: | D8; Ubiquitin-activating enzyme E1 homolog |
| Protein Family: | Ubiquitin-like modifier-activating enzyme |
| UniProt Gene Name: | UBA7 |
| UniProt Entry Name: | UBA7_HUMAN |
Related Products
Anti-UBA7 Antibody (CAB9142)
€99 - €349
OverviewProduct Name:UBA7 Rabbit pAbProduct Code:CAB9142Size:20uL, 50uL, 100uLSynonyms:UBA7, D8, UBA1B, UBE1L, UBE2App
CAB9142
