Anti-Mouse CD120b (TNFR2) In Vivo Antibody

Product Name:	Anti-Mouse CD120b (TNFR2) In Vivo Antibody - Low Endotoxin
Product Code:	IVMB0098
Size:	1mg, 5mg, 25mg, 50mg, 100mg
Clone:	TR75-54.7
Protein:	TNFR2
Product Type:	Monoclonal Antibody
Synonyms:	Tumor Necrosis Factor Receptor II, p75, CD120b, TBPII, TNF-R75, TNFBR, TNFR2, TNFR80, p75TNFR
Isotype:	Armenian Hamster IgG
Reactivity:	Mouse
Immunogen:	Purified Recombinant Mouse TNF R2
Applications:	B, IP, WB
Formulation:	This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added.
Endotoxin Level:	< 1.0 EU/mg as determined by the LAL method
Purity:	≥95% monomer by analytical SEC >95% by SDS Page
Preparation:	Functional grade preclinical antibodies are manufactured in an animal free facility using only In vitro protein free cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates.
Storage and Handling:	Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.

Product Code	Product Name	Endotoxin Level
IVMB0098	Anti-Mouse CD120b (TNFR2) In Vivo Antibody - Low Endotoxin	Low
IVMB0099	Anti-Mouse CD120b (TNFR2) In Vivo Antibody - Ultra Low Endotoxin	Ultra Low

Applications:	B, IP, WB
Reactivity:	Mouse

Host Species:	Armenian Hamster
Specificity:	Anti-Mouse CD120 recognizes Mouse CD120. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Antigen Distribution:	Variety of cell types at low levels
Immunogen:	Purified Recombinant Mouse TNF R2
Concentration:	≥ 5.0 mg/ml
Endotoxin Level:	< 1.0 EU/mg as determined by the LAL method
Purity:	≥95% monomer by analytical SEC >95% by SDS Page
Formulation:	This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added.
Preparation:	Functional grade preclinical antibodies are manufactured in an animal free facility using only In vitro protein free cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates.
Storage and Handling:	Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.

Tumor necrosis factor receptor II (TNF-RII) is present on most cell types1 and is considered to play a prominent role in stimulation by TNF-alpha. TNFRII proteins are expressed by hematopoietic cells including macrophages, neutrophils, lymphocytes, thymocytes and mast cells. It is expressed by a variety of other cell types including endothelial cells, cardiac myocytes and prostate cells.2

Technical Datasheet:	View
Protein:	TNFR2
Function:	Apoptosis, NF-κB activation, inflammation, tumor necrosis, cell differentiation
Ligand/Receptor:	TNF-α, LT-α (TNF-β)
Research Area:	Immunology, Innate Immunity

Armenian Hamster IgG Isotype Control
Clone	PIP
Isotype	Armenian Hamster IgG
Endotoxin Level	Low Endotoxin

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