Immunology

system_update_altDatasheetHuman NCR3/NKp30 Recombinant Protein Natural Cytotoxicity Triggering Receptor 3 (NCR3) along with NKp44 and NKp46 constitute a group of receptors termed “Natural Cytotoxicity Receptors”. They play a major role in triggering...

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system_update_altDatasheetHuman REG3G/PAPB Recombinant Protein Pancreatitis-associated protein IB; Regenerating islet-derived protein III-gamma; is a secreted protein which contains 1 C-type lectin domain. It is expressed almost exclusively in the...

system_update_altDatasheetHuman 2B4/CD244 Recombinant Protein Natural killer cell receptor 2B4 is a type I transmembrane glycoprotein in the SLAM subgroup of the CD2 protein family.2B4 interacts with CD48, while other SLAM family proteins interact...

system_update_altDatasheetHuman OX40/TNFRSF4 Recombinant Protein OX40; also termed CD134 and TNFRSF4; is a T cell co-stimulatory molecule of the TNF receptor superfamily which plays a key role in the survival and homeostasis of effector and memory T...

system_update_altDatasheetHuman CD40/TNFRSF5 Recombinant Protein CD40 is a Type I Transmembrane Glycoprotein that belongs to the TNF Receptor Superfamily. CD40 is expressed in B cells; follicular dendritic cells; dendritic cells; activated monocytes;...

system_update_altDatasheetHuman PD-L1/B7-H1/CD274 Recombinant Protein CD274; also known as B7-H1 or programmed death ligand 1 (PD-L1); is a 40 kD type I transmembrane protein and a member of the B7 family within the immunoglobulin receptor superfamily...

system_update_altDatasheetHuman RNASET2 Recombinant Protein RNASET2 (ribonuclease T2) is an enzyme which belongs to the RNase T2 family. It is highly expressed in the temporal lobe and fetal brain. RNASET2 gene is a novel member of the...

system_update_altDatasheetHuman PD-L2/CD273 Recombinant Protein Programmed Cell Death 1 Ligand 2 (PDCD1LG2) is a member of the BTN/MOG family. PDCD1LG2 contains one Ig-like C2-type domain and one Ig-like V-type domain. PDCD1LG2 is highly expressed in the...

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system_update_altDatasheetHuman ACY3 Recombinant Protein Aspartoacylase 3, also known as ACY3, N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming), Acylase III, Aminoacylase-3, Aspartoacylase-2, Aspartoacylase-2, HCV core-binding protein 1...

system_update_altDatasheetHuman LIMP-2/LIMPII Recombinant Protein Scavenger Receptor Class B Member 2 (SCARB2) is a type III multi-pass membrane glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes on all tissues and...

system_update_altDatasheetHuman CD3 Epsilon/CD3E Recombinant Protein T-Cell Surface Glycoprotein CD3 ? Chain (CD3?) is a single-pass type I membrane protein. CD3? contains 1 Ig-like (immunoglobulin-like) domain and 1 ITAM domain. CD3? is a polypeptide...

system_update_altDatasheetHuman BTN3A3 Recombinant Protein Tumor necrosis factor receptor superfamily; member 19 (TNFRSF19); also known as TAJ-alpha or TROY; is a member of the TNF-receptor superfamily. TNFRSF19/TROY expression is detected in the...

system_update_altDatasheetHuman TIM-3/HAVCR2 Recombinant Protein Hepatitis A virus cellular receptor 2 (HAVCR2) is a single-pass type I membrane protein and it contains 1 Ig-like V-type (immunoglobulin-like) domain. The protein belongs to the...

system_update_altDatasheetHuman SLAMF6/Ly108 Recombinant Protein SLAM Family Member 6 (SLAMF6) is a single-pass type I membrane protein that belongs to the SLAM subgroup of the CD2 family. Human SLAMF6/ NTB-A contains a 205 amino acid extracellular...

system_update_altDatasheetHuman SLAMF5/CD84 Recombinant Protein SLAM family member 5 (SLAMF5/CD84) is a type I transmembrane protein in the SLAM subgroup of the CD2 family. SLAM family proteins regulate multiple aspects of immune system function. Mature...

system_update_altDatasheetHuman TIM-3/HAVCR2 Recombinant Protein Hepatitis A virus cellular receptor 2 (HAVCR2) is a single-pass type I membrane protein and it contains 1 Ig-like V-type (immunoglobulin-like) domain. The protein belongs to the...

system_update_altDatasheetHuman CD200R1 Recombinant Protein Cell surface glycoprotein CD200 Receptor 1 (CD200R1) is the receptor for the CD200 (OX-2) membrane glycoprotein. CD200R1 contains one C2- type Ig-like domain and one V-type Ig-like domain within...

system_update_altDatasheetHuman OX40/TNFRSF4 Recombinant Protein OX40; also termed CD134 andT NFRSF4; is a Tcellco-stimulatory molecule of the TNF receptor superfamily which plays a key role in the survival and homeostasis of effector and memory T cells...

system_update_altDatasheetHuman SAA2/Serum Amyloid A2 Recombinant Protein Serum amyloid A-2 protein (SAA2) belongs to the SAA family. It expressed by the liver and secreted in plasma. SAA2 functions as major acute phase reactant and could works as...

system_update_altDatasheetHuman CD19/Leu2 Recombinant Protein CD19 is a single-pass type I membrane protein containing 2 Ig-like C2-type (immunoglobulin-like) domains. CD19 is expressed on follicular dendritic cells and B cells. In fact; it is present on...

system_update_altDatasheetHuman SAA4 Recombinant Protein Serum Amyloid A-4 Protein (SAA4) is a member of the SAA family. SAA proteins are a family of apolipoproteins associated with high-density lipoprotein (HDL) in plasma. SAA4 is constitutively...

system_update_altDatasheetHuman STAT3 Recombinant Protein Signal Transducer and Activator of Transcription 3 (STAT3) belongs to the transcription factor STAT family. STAT3 contains one SH2 domain and is a transcription factor expressed in most cell types...

system_update_altDatasheetHuman ALCAM/CD166 Recombinant Protein Activated leukocyte cell adhesion molecule (ALCAM), also named as CD166 and MEMD, is a typeI transmembrane glycoprotein of immunoglobulin superfamily, which mediates homotypic and...

system_update_altDatasheetHuman CD32b/FCGR2B Recombinant Protein The Lutheran (Lu) blood group and basal cell adhesion molecule (BCAM) antigens are both carried by 2 glycoprotein isoforms of the immunoglobulin superfamily representing receptors for the...

system_update_altDatasheetHuman CD160/BY55 Recombinant Protein CD160 antigen is a Lipid-anchor that exists as a disulfide-linked homomultimer. CD160 contains one Ig-like V-type domain. The human CD160 precursor is a cysteine-rich;...

system_update_altDatasheetHuman CD80/B7 Recombinant Protein Cluster of Differentiation 80, also called B7-1, is a member of cell surface immunoglobulin superfamily which plays key, yet distinct roles in the activation of T cells. It is the ligand for two...

system_update_altDatasheetHuman CD150/SLAMF1 Recombinant Protein SLAM-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAM signaling are likely to exist: one in which the inhibitor SH2D1A acts as a...

system_update_altDatasheetHuman SGTA Recombinant Protein Small Glutamine-Rich Tetratricopeptide Repeat-Containing Protein ? (SGTA) is an ubiquitously expressed protein which belongs to the SGT Family. SGTA contains three TPR Protein-Protein Interaction...

system_update_altDatasheetHuman Serum Amyloid A1/SAA1 Recombinant Protein Serum Amyloid A1 Protein (SAA1) is an acute phase apolipoprotein reactant that is produced predominantly by hepatocytes and is under the regulation of inflammatory cytokines. SAA...

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system_update_altDatasheetHuman SMAD3 Recombinant Protein Mothers against decapentaplegic homolog 3(SMAD3) is a cytoplasm protein which belongs to the dwarfin/SMAD family. Smad proteins undergo rapid nuclear translocation upon stimulation by transforming...

system_update_altDatasheetHuman SLAMF6/Ly108 Recombinant Protein SLAM Family Member 6 (SLAMF6) is a 60 kD single-pass type I membrane protein that belongs to the SLAM subgroup of the CD2 family. Human SLAMF6/ NTB-A contains a 205 amino acid extracellular...

system_update_altDatasheetHuman RNASET2 Recombinant Protein RNASET2 (ribonuclease T2) is an enzyme which belongs to the RNase T2 family. It is highly expressed in the temporal lobe and fetal brain. RNASET2 gene is a novel member of the...

system_update_altDatasheetAMBP/Alpha 1 Microglobulin Recombinant Protein Protein AMBP belongs to the calycin superfamily and Lipocalin family. AMBP can be cleaved into three chains: ?-1-microglobulin, inter-?-trypsin inhibitor light chain and trypstatin...

system_update_altDatasheetHuman TNFRSF13B/TACI/CD267 Recombinant Protein Tumor necrosis factor receptor superfamily, member 13B (TNFRSF13B) also known as Transmembrane activator and CAML interactor (TACI) and CD267 antigen, is a member of the tumor...

system_update_altDatasheetHuman CD7/GP40 Recombinant Protein T-Cell Antigen CD7 is a single-pass type I membrane protein that that belongs to the the immunoglobulin superfamily. Human CD7 is synthesized as a 240 amino acid precursor that contains a 25...

system_update_altDatasheetHuman MICA Recombinant Protein MHC class I polypeptide-related sequence A, also known as MIC-A, PERB11.1 and MICA, is a single-pass type I membrane protein which belongs to the MHC class I family of MIC subfamily. MICA contains...

system_update_altDatasheetHuman SLAMF6/Ly108 Recombinant Protein SLAM family member 6; also known as Activating NK receptor; NK-T-B-antigen; NTB-A; SLAMF6; KALI and Ly108; is a single-pass type I membrane protein which belongs to the CD2 subfamily of the...

system_update_altDatasheetHuman SLAMF6/Ly108 Recombinant Protein SLAM family member 6; also known as Activating NK receptor; NK-T-B-antigen; NTB-A; SLAMF6; KALI and Ly108; is a single-pass type I membrane protein which belongs to the CD2 subfamily of the...

system_update_altDatasheetHuman TIM-3/HAVCR2 Recombinant Protein T-Cell Membrane Protein 3 (TIM3) is a single-pass type I membrane protein that belongs to the TIM family of immunoglobulin superfamily. TIM3 includes a signal sequence (aa 1-21); an...

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system_update_altDatasheetHuman SerpinA3/AACT Recombinant Protein Serpin A3 belongs to the Serpin superfamily of serine protease inhibitors. Serpin A3 has been shown to inhibit some serine proteases, such as neutrophil cathepsin G and mast cell chymase...

system_update_altDatasheetHuman SLPI Recombinant Protein Secretory leukoprotease inhibitor (SLPI); also called antileukoprotease (ALP); is a 12-kDa; nonglycosylated serine protease inhibitor present in mucous secretions. It is thought to play a role in...

system_update_altDatasheetHuman CD4/LEU3 Recombinant Protein CD4 is an approximately 55?kDa type?I transmembrane glycoprotein that is expressed predominantly on thymocytes and a subset of mature T?lymphocytes. It is a standard phenotype marker for the...

system_update_altDatasheetHuman SerpinA1/A1AT Recombinant Protein Serpin A1 is a prototype member of the Serpin superfamily of the serine protease inhibitors. As one of the most abundant proteinase inhibitors in the circulation, it is synthesized in...

system_update_altDatasheetHuman Factor D Recombinant Protein Complement factor D; also known as adipsin; is a member of the chymotrypsin family of serine proteases; which plays an essential role in host defense as the rate-limiting enzyme in the...

system_update_altDatasheetHuman BTLA/CD272 Recombinant Protein B- and T-Lymphocyte Attenuator (BTLA) is a single-pass type I membrane protein containing 1 Ig-like V-type (immunoglobulin-like) domain. BTLA expression is induced during activation of T...

system_update_altDatasheetHuman M-CSF/CSF1 Recombinant Protein Macrophage Colony-Stimulating Factors (m-csf) are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the...

system_update_altDatasheetHuman B7-H4/VTCN1 Recombinant Protein B7 Homolog 4 (B7-H4) is glycosylated member of the B7 family of immune costimulatory proteins. Mature human B7-H4 consists of a 235 amino acid (aa) extracellular domain (ECD) with two...

system_update_altDatasheetHuman B7-H4/VTCN1 Recombinant Protein B7 Homolog 4 (B7-H4) is glycosylated member of the B7 family of immune costimulatory proteins. Mature human B7-H4 consists of a 235 amino acid (aa) extracellular domain (ECD) with two...

system_update_altDatasheetHuman KEAP1/INRF2 Recombinant Protein Kelch-like ECH-associated protein 1; also known as cytosolic inhibitor of Nrf2; Kelch-like protein 19; KEAP1 and INRF2; is a cytoplasm and nucleus protein which contains one BACK (BTB/Kelch...

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system_update_altDatasheetHuman BLNK/Ly-57 Recombinant Protein B-Cell Linker Protein (BLNK) is a cell membrane protein which contains 1 SH2 domain. BLNK is expressed in B cells and fibroblast cell lines, playing a important role in B cell receptor...

system_update_altDatasheetHuman MBL2/MBL/COLEC1 Recombinant Protein Mannose-Binding Protein C (MBP-C) belongs to the Collectin family of innate immune defense proteins. MBL binds to an array of carbohydrate patterns on pathogen surfaces. Collectin family...

system_update_altDatasheetHuman MD1 Recombinant Protein LY86 is a protein that in humans is encoded by the LY86 gene; which May cooperate with CD180 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) and cytokine...

system_update_altDatasheetHuman MASP1 Recombinant Protein Mannan-Binding Lectin Serine Protease 1 (MASP-1) belongs to the peptidase S1 family. MASP1 contains two CUB domains, one EGF-like domain, one peptidase S1 domain and two Sushi (CCP/SCR) domains...

system_update_altDatasheetHuman CD8 beta/CD8B Recombinant Protein CD8B (CD8b molecule); also known as P37 and LEU2; contains 1 Ig-like V-type (immunoglobulin-like) domain. The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T...

system_update_altDatasheetBeta-2-Microglobulin/B2M Recombinant Protein β-2-Microglobulin (B2M) is a secreted protein with 1 Ig-like C1-type (immunoglobulin-like) domain which belongs to the beta-2-microglobulin family. B2M component of major...

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system_update_altDatasheetHuman SLPI Recombinant Protein Secretory leukoprotease inhibitor (SLPI); also called antileukoprotease (ALP); is a 12-kDa; nonglycosylated serine protease inhibitor present in mucous secretions. It is thought to play a role in...

system_update_altDatasheetHuman BTN3A1/CD277 Recombinant Protein Butyrophilin Subfamily 3 Member A1 (BTN3A1/CD277) is a type I transmembrane glycoprotein member of the Ig superfamily. It is expressed on a wide variety of immune cells. Similar to BTN3A2...

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system_update_altDatasheetHuman CSF1R/CD115 Recombinant Protein Macrophage colony-stimulating factor 1 receptor (CSF1R) is a member of the type III subfamily of receptor tyrosine kinases that also includes receptors for SCF and PDGF. These receptors each...

system_update_altDatasheetHuman Calnexin/CANX Recombinant Protein Calnexin/CANX is a single-pass type I membrane protein which belongs to the calreticulin family. It consists of a large N-terminal calcium-binding lumenal domain, a single transmembrane...

system_update_altDatasheetHuman CAMK1D Recombinant Protein CAMK1D is a serine threonine kinase that is a member of the calcium?calmodulin-dependent protein kinase family. It contains a protein kinase domain. CAMK1D expressed in polymorphonuclear...

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system_update_altDatasheetHuman KARS Recombinant Protein Lysine-tRNA ligase, also known as Lysyl-tRNA synthetase, LysRS, KARS and KIAA0070, belongs to the class-II aminoacyl-tRNA synthetase family. The N-terminal cytoplasmic domain (1-65) is a functional...

system_update_altDatasheetHuman IL2RG/CD132 Recombinant Protein The common gamma chain (γc) (or CD132); also known as interleukin-2 receptor subunit gamma or IL2RG; is a member of the type I cytokine receptor family expressed on most lymphocyte...

system_update_altDatasheetHuman IL2RG/CD132 Recombinant Protein The common gamma chain (γc) (or CD132); also known as interleukin-2 receptor subunit gamma or IL2RG; is a member of the type I cytokine receptor family expressed on most lymphocyte...

system_update_altDatasheetHuman CD160/BY55 Recombinant Protein CD160 antigen is a Lipid-anchor that exists as a disulfide-linked homomultimer. CD160 contains one Ig-like V-type domain. The human CD160 precursor is a cysteine-rich;...

system_update_altDatasheetHuman MSN/Moesin Recombinant Protein Moesin is a member of the ERM family which includes ezrin and radixin. ERM proteins, highly related members of the larger protein 4.1 superfamily, can exist in an active or inactive...

system_update_altDatasheetHuman IL2RG/CD132 Recombinant Protein IL2RG contains one fibronectin type-III domain. IL2RG is an important signaling component of many interleukin receptors; including those of interleukin -2; -4; -7 and -21; and is thus...

system_update_altDatasheetHuman REG3G/PAPB Recombinant Protein Pancreatitis-associated protein IB; Regenerating islet-derived protein III-gamma; is a secreted protein which contains 1 C-type lectin domain. It is expressed almost exclusively in the...

system_update_altDatasheetHuman NKG2D/CD314 Recombinant Protein NKG2-D type II integral membrane protein (NKG2D) is a type II transmembrane glycoprotein which belongs to the CD94/NKG2 family. NKG2D is expressed on natural killer (NK) cells; CD8+...

system_update_altDatasheetHuman CD40/TNFRSF5 Recombinant Protein CD40 is a Type I Transmembrane Glycoprotein that belongs to the TNF Receptor Superfamily. CD40 is expressed in B cells; follicular dendritic cells; dendritic cells; activated monocytes;...

system_update_altDatasheetHuman LAT2 Recombinant Protein Linker for Activation of T-Cells Family Member 2 (LAT2) is a single-pass type III membrane protein. LAT2 is highly expressed in the spleen, peripheral blood lymphocytes, and germinal centers of...

system_update_altDatasheetHuman IL1F6/IL36A Recombinant Protein Interleukin-1 family member 6 (IL-1F6); also known as interleukin 36; alpha (IL36A); is a pro-inflammatory cytokine which plays an important role in innate and adaptive immunity. IL-1F6...

system_update_altDatasheetHuman CD40/TNFRSF5 Recombinant Protein CD40 is a Type I Transmembrane Glycoprotein that belongs to the TNF Receptor Superfamily. CD40 is expressed in B cells; follicular dendritic cells; dendritic cells; activated monocytes;...

system_update_altDatasheetHuman CD86/B7-2 Recombinant Protein The protein is the receptor that involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. It may play a critical...

system_update_altDatasheetHuman VAPB Recombinant Protein vesicle-associated membrane protein-associated protein B/C (VAPB) is presents in mitochondria-associated membranes that are endoplasmic reticulum membrane regions closely apposed to the outer...

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system_update_altDatasheetHuman LMIR2/CD300C Recombinant Protein CD300C is a single-pass type I membrane protein which belongs to the immunoregulatory signaling (IRS) family. CD300C contains one Ig-like V-type domain and is present on the surface of...

system_update_altDatasheetHuman CD32a/FCGR2A Recombinant Protein Receptors for the Fc region of IgG (Fc?R) are members of the Ig superfamily that function in the activation or inhibition of immune responses. Human Fc?Rs are divided into three classes...

system_update_altDatasheetHuman LMIR2/CD300C Recombinant Protein CD300C is a single-pass type I membrane protein which belongs to the immunoregulatory signaling (IRS) family. CD300C contains one Ig-like V-type domain and is present on the surface of...

system_update_altDatasheetHuman ULBP2/N2DL-2 Recombinant Protein NKG2D ligand 2; also known as N2DL-2; NKG2DL2; ALCAN-alpha; Retinoic acid early transcript 1H; UL16-binding protein 2; ULBP2 and N2DL2; is cell membrane protein which belongs to...

system_update_altDatasheetHuman LILRB2/CD85d Recombinant Protein Members of the immunoglobulin-like transcript (ILT) family are activating and inhibitory immunoreceptors whose genes are located same locus that encodes killer cell Ig-like receptors (KIR)...

system_update_altDatasheetBeta-2-Microglobulin/B2M Recombinant Protein β-2-Microglobulin (B2M) is a secreted protein with 1 Ig-like C1-type (immunoglobulin-like) domain which belongs to the beta-2-microglobulin family. B2M component of major...

system_update_altDatasheetHuman LILRA2/ILT1 Recombinant Protein Leukocyte Immunoglobulin-Like Receptor Subfamily A Member 2 (LILRA2) is a single-pass type I membrane protein. LILRA2 is expressed predominantly on monocytes and B cells, and at lower levels...

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system_update_altDatasheetHuman VSIG4 Recombinant Protein VSIG4 (V-set and immunoglobulin domain containing 4); also known as complement receptor of the immunoglobulin superfamily (CRIg) and Z39Ig; is a type I  transmembrane glycoprotein. It is a...

system_update_altDatasheetHuman PADI4 Recombinant Protein Protein-Arginine Deiminase Type-4 (PADI4) belongs to the Protein Arginine Deiminase family. PADI4 is expressed in eosinophils and neutrophils, but it is not expressed in peripheral monocytes or...

system_update_altDatasheetHuman ETS1/EWSR2 Recombinant Protein ETS1 Protein (ETS1) is a nuclear protein that belongs to the ETS family. Members of this family recognize the core consensus DNA sequence GGAA/T in target genes. Proteins function either as...

system_update_altDatasheetHuman CRP/C-Reactive Recombinant Protein C-reactive protein (CRP) belongs to the pentaxin family. CRP is a secreted protein found in plasma. It can binds two calcium ions per subunit.CRP can promotes phagocytosis, bacterial...

system_update_altDatasheetHuman CD19/Leu2 Recombinant Protein The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD...