Metabolism

system_update_altDatasheetHuman ROR1 Recombinant Protein Receptor tyrosine kinase-like orphan receptor 1 (ROR1); also known as neurotrophic tyrosine kinase; it is a member of the ROR family within receptor tyrosine kinases (RTK) superfamily. Human ROR1...

system_update_altDatasheetHuman GSS Recombinant Protein Glutathione Synthetase belongs to the eukaryotic GSH synthase family. Glutathione Synthetase is the second enzyme in the glutathione biosynthesis pathway. It catalyses the condensation of...

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system_update_altDatasheetHuman GOT1 Recombinant Protein Glutamate Oxaloacetate Transaminase 1 (GOT1) is a cytoplasmic protein. GOT1 belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. GOT1 is a pyridoxal phosphate-dependent...

system_update_altDatasheetHuman G6PD Recombinant Protein Glucose-6-Phosphate 1-Dehydrogenase (G6PD) is a cytosolic enzyme that belongs to the glucose-6-phosphate dehydrogenase family. G6PD participates in the pentose phosphate pathway that supplies...

system_update_altDatasheetHuman Sialidase/NEU Recombinant Protein Sialidase-1 belongs to the N-acetyl-a neuraminidase family. Sialidase-1 is expressed in many tissues; it is highly expressed in the pancreas, and weakly expressed in the brain. Sialidase-1...

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system_update_altDatasheetHuman GGPS1 Recombinant Protein Geranylgeranyl pyrophosphate synthase (GGPS1) is a member of the FPP/GGPP synthase family. GGPS1 is highly expressed in testis, heart and skeletal muscle. GGPS1 is localized in the cytoplasm and...

system_update_altDatasheetHuman ACO1/irp1 Recombinant Protein Aconitase 1(ACO1) or IRP1 is one member of the aconitase family that contains a diverse group of iron-sulphur(Fe-S) isomerases and two types of iron regulatory protein. Aconitase exits in two...

system_update_altDatasheetHuman Gastric Lipase/LIPF Recombinant Protein Gastric Triacylglycerol Lipase (LIPF) belongs to the AB hydrolase superfamily. LIPF is an important lipase during the digestion of dietary lipids in cystic fibrosis. LIPF is involved...

system_update_altDatasheetHuman SerpinH1/SERPINH1 Recombinant Protein Serpin H1 is a serine proteinase inhibitors Which belongs to the serpin family. Serpin H1 is induced by heat shock. Serpin H1 localizes to the endoplasmic reticulum lumen and binds...

system_update_altDatasheetHuman PGD2 Synthase/PTGDS Recombinant Protein Prostaglandin-H2 D-Isomerase (PTGDS) belongs to the Lipocalin family of calycin superfamily. PTGDS is preferentially expressed in the brain. PTGDS catalyzes the conversion of PGH2 to...

system_update_altDatasheetHuman PKM2 Recombinant Protein Pyruvate kinase isozymes M2 also known as pyruvate kinase muscle isozyme 2 (PKM2); pyruvate kinase type K; cytosolic thyroid hormone-binding protein (CTHBP); thyroid hormone-binding protein 1...

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system_update_altDatasheetHuman GALM Recombinant Protein Galactose Mutarotase (GALM) is a cytoplasmic enzyme that belongs to the Aldose Epimerase family. GALM is a Mutarotase that converts ?-Aldose to the β-Anomer. GALM is active on D-Glucose,...

system_update_altDatasheetApolipoprotein A-I/ApoAI Recombinant Protein Apolipoprotein A1 (APOA1) is a secreted protein which belongs to the Apolipoprotein A1/A4/E family. APOA1 is the major protein component of high density lipoprotein (HDL) in plasma...

system_update_altDatasheetAPOB/Apolipoprotein B00 Recombinant Protein Apolipoprotein B is a major protein constituent of chylomicrons (apo B-48), LDL (apo B-100) and VLDL (apo B-100). Apo B-100 functions as a recognition signal for the cellular binding...

system_update_altDatasheetHuman SHMT1 Recombinant Protein Serine Hydroxymethyltransferase Cytosolic (SHMT1) is a member of the SHMT family. SHMT1 is a cytoplasmic protein and exists as a homotetramer. SHMT1 catalyzes the reversible conversion of serine...

system_update_altDatasheetFumarylacetoacetase/FAH Recombinant Protein Fumarylacetoacetase belongs to the FAH family. Fumarylacetoacetase is primary expressed in liver and kidney. It exists as a homodimer and catalyzes the hydrolysis of...

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system_update_altDatasheetHuman ALDOA Recombinant Protein Fructose Bisphosphate Aldolase A (ALDOA) belongs to the class I fructose-bisphosphate aldolase family. ALDOA is a glycolytic enzyme that catalyzes the reversible conversion of...

system_update_altDatasheetHuman CYB5R1 Recombinant Protein Tyrosinase-related protein 1, also known as TYRP1 or TRP1, is a melanosomal enzyme that belongs to the tyrosinase family and plays an important role in the melanin biosynthetic pathway. Mutations...

system_update_altDatasheetHuman CROT Recombinant Protein Carnitine octanoyltransferase (CROT or COT), also known as octanoyl-CoA: L-carnitine O-octanoyltransferase, medium-chain/long-chain carnitine acyltransferase, and carnitine medium-chain...

system_update_altDatasheetHuman MAA/GSTZ1 Recombinant Protein Maleylacetoacetate Isomerase (MAAI) belongs to the Glutathione S-Transferase super-family. MAAI encodes multifunctional enzymes in the detoxification of electrophilic molecules by conjugation...

system_update_altDatasheetHuman MDH2 Recombinant Protein Malate dehydrogenase, mitochondrial is a 338 amino acids protein that belongs to the LDH/MDH superfamily. MDH type 1 family. MDH2 catalyzes the reversible oxidation of malate to oxaloacetate,...

system_update_altDatasheetHuman MDH1 Recombinant Protein Malate Dehydrogenase, Cytoplasmic (MDH1) is an enzyme which belongs to the MDH Type 2 sub-family of LDH/MDH superfamily. MDH1 is involved in the Citric Acid Cycle that catalyzes the conversion of...

system_update_altDatasheetHuman AMY2A/Alpha-amylase Recombinant Protein Alpha-amylase is the major form of amylase found in humans and other mammals. Amylases are secreted proteins that hydrolyze 1,4-alpha-glucoside bonds in oligosaccharides and...

system_update_altDatasheetHuman PGD Recombinant Protein 6-phosphogluconate dehydrogenase(PGD) is a cytoplasm-located protein; and belongs to the 6-phosphogluconate dehydrogenase family. 6PGD is the second dehydrogenase in the pentose phosphate shunt. It...

system_update_altDatasheetOverviewProduct Name:Human IDH1 Recombinant Protein (RPES3967)Product Code:RPES3967Size:10µgSpecies:HumanExpressed Host:E.coliSynonyms:Isocitrate Dehydrogenase [NADP] Cytoplasmic, IDH, Cytosolic NADP-Isocitrate Dehydrogenase,...

system_update_altDatasheetHuman ROR2 Recombinant Protein Receptor Tyrosine Kinaselike Orphan Receptor 2(ROR2) belongs to the protein kinase superfamily, Tyr protein kinase family and ROR subfamily. It is a member of the ROR family of receptor tyrosine...

system_update_altDatasheetHuman PAH/PH Recombinant Protein PAH (phenylalanine hydroxylase), also known as PH, belongs to the biopterin-dependent aromatic amino acid hydroxylase family. It contains 1 ACT domain, N-terminal region of PAH is thought to...

system_update_altDatasheetHuman GMPR Recombinant Protein GMPR; also known as GMPR1; belongs to the IMPDH/GMPR family. This family of enzymes includes IMP dehydrogenase and GMP reductase. These enzymes are involved...

system_update_altDatasheetHuman DCXR Recombinant Protein L-Xylulose Reductase is an enzyme that belongs to the Short-Chain Dehydrogenases/Reductases (SDR) family. L-Xylulose Reductase is responsible for the metabolism of Xylulose, converting it into...

system_update_altDatasheetHuman FBPase 1/FBP1 Recombinant Protein Fructose-1;6-bisphosphatase 1(FBP1) is a homotetramer protein and belongs to the FBPase class 1 family. It involves in carbohydrate biosynthesis; gluconeogenesis pathway. FBP1 is a...

system_update_altDatasheetHuman FBPase 1/FBP1 Recombinant Protein Fructose-1;6-Bisphosphatase 1 (FBPase 1) is a member of the FBPase class 1 family. FBPase 1 is a gluconeogenesis regulatory protein; which catalyzes the hydrolysis of fructose...

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system_update_altDatasheetHuman Galactolipase/PLRP2 Recombinant Protein Galactolipase; also known as PNLIPRP2; is a lipase with broad substrate specificity. It can hydrolyze both phospholipids and galactolipids. Galactolipase acts preferentially on...

system_update_altDatasheetHuman PGD Recombinant Protein 6-phosphogluconate dehydrogenase(PGD) is a cytoplasm-located protein; and belongs to the 6-phosphogluconate dehydrogenase family. 6PGD is the second dehydrogenase in the pentose phosphate shunt. It...

system_update_altDatasheetHuman QPRT/QPRTase Recombinant Protein Nicotinate-Nucleotide Pyrophosphorylase (QPRT) belongs to the nadC/modD family. QPRT plays an improtant role in catabolism of quinolinate which acts as a potent endogenous exitotoxin to...

system_update_altDatasheetHuman PKLR Recombinant Protein Pyruvate Kinase Isozymes R/L (PKLR) belongs to the pyruvate kinase family, There are 4 isozymes of pyruvate kinase in mammals: L, R, M1 and M2. L type is major isozyme in the liver; R is found in...

system_update_altDatasheetHuman LTA4H Recombinant Protein LTA4H, which is short for Leukotriene A-4 hydrolase, is a 611 aa. protein. It belongs to the peptidase M1 family, and exists in cytoplasm. This protein has at least 4 isforms produced by...

system_update_altDatasheetHuman BBOX1/Gamma-BBH Recombinant Protein BBOX1, also known as gamma-BBH, belongs to the gamma-BBH/TMLD family. It is highly expressed in kidney and moderately expressed in liver. BBOX1 catalyzes the formation of...

system_update_altDatasheetHuman PCBD1 Recombinant Protein Pterin-4-?-Carbinolamine Dehydratase (PCBD1) is the founding member of the Pterin-4-?-Carbinolamine Dehydratase Family. PCBD1 is involved in Tetrahydrobiopterin biosynthesis. It seems to prevent...

system_update_altDatasheetHuman BPGM Recombinant Protein Bisphosphoglycerate Mutase (BPGM) is a member of the Phosphoglycerate Mutase family and BPG-Dependent PGAM subfamily. BPGM is a multifunctional enzyme. BPGM catalyzes 2,3-DPG synthesis via its...

system_update_altDatasheetHuman PLA2G7/Lp-PLA2 Recombinant Protein Platelet-Activating Factor Acetylhydrolase (PAFAH) is a secreted enzyme which belongs to the AB hydrolase superfamily and Lipase family and catalyzes the degradation of...

system_update_altDatasheetHuman PPP1R1A Recombinant Protein Protein Phosphatase 1 Regulatory Subunit 1A (PPP1R1A) is an inhibitor of protein-phosphatase 1. PPP1R1A is a cellular regulator of eIF2 alpha phosphorylation. In hormonal control of glycogen...

system_update_altDatasheetHuman ST8SIA1 Recombinant Protein ?-N-Acetylneuraminide ?-2,8-Sialyltransferase (ST8SIA1) belongs to the glycosyltransferase 29 family. ST8SIA1 is a sialytransferase that catalyzes the transfer of sialic acid from CMP-sialic...

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system_update_altDatasheetHuman LCAT Recombinant Protein Lipase family. The gene encoding this protein is expressed mainly in brain, liver and testes,followed by secreting into plasma and cerebral spinal fluid. The esterification of cholesterol is...

system_update_altDatasheetHuman ERP44 Recombinant Protein Endoplasmic reticulum resident protein 44 (TXNDC4) is is a 406 amino acid protein that contains one thioredoxin domain. TXNDC4 mediates thiol-dependent retention in the early secretory pathway and...

system_update_altDatasheetHuman beta Amylase/AMY2 Recombinant Protein Alpha-amylase 2B is an enzyme that in humans is encoded by the AMY2B gene. Alpha-amylase 2B is a secreted protein and belongs to the glycosyl hydrolase 13 family. It hydrolyzes...

system_update_altDatasheetHuman ASS1 Recombinant Protein Argininosuccinate Synthase (ASS1) is an urea cycle enzyme with a tetrameric structure composed of identical subunits. ASS1 is involved in the synthesis of arginine and catalyzes that condensation...

system_update_altDatasheetHuman Ketohexokinase/KHK Recombinant Protein Ketohexokinase, also known as Hepatic fructokinase, is a member of the carbohydrate kinase PfkB family. It exits as a homodimer and most abundant in liver, kidney, gut, spleen and...

system_update_altDatasheetHuman Apolipoprotein E/ApoE Recombinant Protein ApoE, a glycoprotein, is a structural component of very low density lipoprotein (vLDL) synthesized by the liver and intestinally synthesized chylomicrons . ApoE is also a...

system_update_altDatasheetHuman SULT1A3 Recombinant Protein Sulfotransferase 1A3/1A4 (SULT1A3) is 295 amino acids in length and localizes to the cytoplasm. It is a member of the Sulfotransferase 1 family. SULT1A3 can be found in the liver, colon, kidney,...

system_update_altDatasheetApolipoprotein C-II/APOC2 Recombinant Protein APOC2 activates the lipoprotein lipase in capillaries, which hydrolyzes triglycerides and thus provides free fatty acids for cells. APOC2 is component of the very low density...

system_update_altDatasheetHuman SULT2A1 Recombinant Protein Bile Salt Sulfotransferase (SULT2A1( is a cytosolic enzyme that belongs to the Sulfotransferase 1 family. SULT2A1 is primarily expressed in the liver and adrenal tissues, and to a lesser extent...

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system_update_altDatasheetApolipoprotein A-I/ApoAI Recombinant Protein Apolipoprotein A1 (APOA1) is a secreted protein which belongs to the Apolipoprotein A1/A4/E family. APOA1 is the major protein component of high density lipoprotein (HDL) in plasma...

system_update_altDatasheetWnt Inhibitory Factor 1/WIF1 Recombinant Protein Wnt Inhibitory Factor 1 (WIF1) is a secreted protein, which binds WNT proteins and inhibits their activities. WNT proteins are extracellular signaling molecules involved in the...

system_update_altDatasheetHuman GALK1/Galactokinase Recombinant Protein Galactokinase; also known as Galactose kinase; GALK and GALK1; is a protein which belongs to the GHMP kinase family and GalK subfamily. Galactokinase / GALK1 is a major...

system_update_altDatasheetHuman IPPI2/IDI2 Recombinant Protein Isopentenyl Pyrophosphate Isomerase 2 (IDI2) belongs to the IPP isomerase type 1 family. Both isozymes, IDI1 and IDI2 are localized to the peroxisome by a PTS1-dependent pathway. IDI2 is...

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system_update_altDatasheetHuman IDH1 Recombinant Protein Isocitrate Dehydrogenase [NADP] Cytoplasmic (IDH1) belongs to the isocitrate and isopropylmalate dehydrogenases family. IDH1 exists as a homodimer; binding one magnesium or manganese ion per...

system_update_altDatasheetHuman EIF1AX Recombinant Protein Eukaryotic Translation Initiation Factor 1A, X-Chromosomal (EIF1AX) is an essential eukaryotic translation initiation factor that belongs to the eIF-1A family. EIF1AX is required for the binding...

system_update_altDatasheetHuman PLA2G2D Recombinant Protein The enzyme oligosaccharyltransferase (dolichyl-diphosphooligosaccharide-protein glycosyltransferase) (DDOST), or 48-kDa subunit (OST48) is one of the catalytic subunits in this complex, exerts a...

system_update_altDatasheetHuman SULT1A1 Recombinant Protein Sulfotransferase 1A1 (SULT1A1) is a cytosolic sulfotransferases that is expressed in the liver; lung; adrenal; brain; platelets; and skin. SULT1A1 is a phenol sulfotransferases with thermostable...

system_update_altDatasheetHuman GRK6/GPRK6 Recombinant Protein G protein-coupled receptor kinase 6, also known as G protein-coupled receptor kinase GRK6, GRK6 and GPRK6, is a lipid-anchor protein which belongs to the protein kinase superfamily,...

system_update_altDatasheetHuman GALK1/Galactokinase Recombinant Protein Galactokinase belongs to the GHMP kinase family and GalK subfamily. Galactokinase is more important to the galactose metabolism pathway. It modifies galactose to create a similar...

system_update_altDatasheetHuman NSE/ENO2 Recombinant Protein Gamma-enolase; also known as Enolase 2; belongs to the enolase family. The alpha/alpha homodimer of ENO2 is expressed in embryo and in most adult tissues. The alpha/beta heterodimer and the...

system_update_altDatasheetHuman dUTPase Recombinant Protein Deoxyuridine 5'-Triphosphate Nucleotidohydrolase Mitochondrial (dUTPase) belongs to the dUTPase family. dUTPase exits as a homotrimer and is involved in nucleotide metabolism. dUTPase produces...

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system_update_altDatasheetHuman MVK/Mevalonate kinase Recombinant Protein Mevalonate kinase belongs to the GHMP kinase family, Mevalonate kinase subfamily. It can be found in a wide variety of organisms from bacteria to mammals. Mevalonate kinase may be...

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system_update_altDatasheetHuman HSP40/DNAJB1 Recombinant Protein DnaJ Homolog Subfamily B Member 1 (DNAJB1) is a member of the heat shock protein family. Heat shock proteins (HSPs) are a highly conserved family of stress response proteins. HSPs function...

system_update_altDatasheetHuman PFK1/PFKM Recombinant Protein PFK1, also known as PFKM, is a regulatory glycolytic enzyme. PFK1 converts fructose 6-phosphate and ATP into fructose 1,6-bisphosphate (through PFK-1), fructose 2,6-bisphosphate (through...

system_update_altDatasheetOverviewProduct Name:AMPK (G1/B1/A1) Recombinant Protein (RPES2438)Product Code:RPES2438Size:20µgSpecies:HumanExpressed Host:Baculovirus-Insect CellsSynonyms:AMPK,AMPKa1Accession:P54619PropertiesSequence:Met 1-Pro 331Fusion...

system_update_altDatasheetHuman RPE Recombinant Protein Ribulose-Phosphate 3-Epimerase (RPE) is a member of the Ribulose-Phosphate 3-Epimerase family. RPE exists as a homodimer and catalyzes the reversible epimerization of D-ribulose 5-phosphate to...

system_update_altDatasheetOverviewProduct Name:AMPK (G1/B2/A2) Recombinant Protein (RPES2416)Product Code:RPES2416Size:20µgSpecies:HumanExpressed Host:Baculovirus-Insect CellsSynonyms:AMPK,AMPKa1Accession:P54619PropertiesSequence:Met 1-Pro 331Fusion...

system_update_altDatasheetHuman HMBS Recombinant Protein Porphobilinogen Deaminase (HMBS) is a member of the HMBS family. PBGD is the third enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of four porphobilinogen...

system_update_altDatasheetHuman ACO2/Aconitase 2 Recombinant Protein Interleukin 10 receptor, beta subunit (IL10RB/IL-10RB) also known as Cytokine receptor family 2 member 4, Interleukin-10 receptor subunit 2, and cytokine receptor family II, member 4,...

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system_update_altDatasheetHuman Dipeptidase 1/DPEP1 Recombinant Protein Dipeptidase 1 (DPEP1) is a kidney membrane enzyme that belongs to the peptidase M19 family. DPEP1 is a homodimer and is inhibited by L-penicillamine. DPEP1 hydrolyzes a variety of...

system_update_altDatasheetHuman UROS/UROIIIS Recombinant Protein Uroporphyrinogen-III Synthase is an enzyme which belongs to the uroporphyrinogen-III synthase family. Uroporphyrinogen-III Synthase is ubiquitous and it is involved in Porphyrin metabolism...

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system_update_altDatasheetHuman UROD Recombinant Protein Uroporphyrinogen decarboxylase (UROD), is an enzyme of the heme biosynthetic pathway which belongs to the uroporphyrinogen decarboxylase family. This enzyme is responsible for catalyzing the...

system_update_altDatasheetHuman DKK2 Recombinant Protein Dickkopf-related protein 2 (DKK2), is a member of the dickkopf family. DKK2 is secreted protein which contains two cysteine rich regions and is involved in embryonic development through its...

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system_update_altDatasheetHuman COQ7 Recombinant Protein Ubiquinone Biosynthesis Protein COQ7 Homolog (COQ7) is a mitochondrion inner membrane and peripheral membrane protein which belongs to the COQ7 family. It is expressed dominantly in heart and...

system_update_altDatasheetADSL/Adenylosuccinate Lyase Recombinant Protein Adenylosuccinate lyase, also known as adenylosuccinase, ADSL or ASL, is an enzyme implicated in the reaction of adenylosuccinat converting to AMP and fumarate as part of the purine...

system_update_altDatasheetHuman DHPS Recombinant Protein Human Deoxyhypusine Synthase (DHS) is vital for the first step of hypusine biosynthesis. DHS catalyzes the NAD-dependent oxidative cleavage of spermidine, the subsequent transfer of the butylamine...

system_update_altDatasheetHuman GALE Recombinant Protein The enzyme UDP-Glucose 4-Epimerase (GALE) is a homodimeric epimerase found in bacterial, plant and mammalian cells. UDP-Glucose 4-Epimerase performs the final step in the Leloir pathway of...

system_update_altDatasheetHuman LYPLA2 Recombinant Protein Acyl-Protein Thioesterase 2 is a cytoplasmic protein that belongs to the AB Hydrolase 2 family. LYPLA2 is a lysophospholipase and hydrolyzes fatty acids from S-acylated cysteine residues in...

system_update_altDatasheetHuman ROR1 Recombinant Protein CD217; also known as Interleukin-17 receptor A; is a T cell expressed pleotropic cytokine with 866 amino acids in length. CD217 functions as receptors for IL17A and IL17F; it binds to IL17A with...

system_update_altDatasheetHuman ROR1 Recombinant Protein Receptor tyrosine kinase-like orphan receptor 1 (ROR1); also known as neurotrophic tyrosine kinase; it is a member of the ROR family within receptor tyrosine kinases (RTK) superfamily. Human ROR1...

system_update_altDatasheetHuman LYPLA1 Recombinant Protein Acyl-Protein Thioesterase 1 (APT-1) is lysophospholipase that belongs to the AB hydrolase 2 family. Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional...

system_update_altDatasheetHuman PLA2G1B/PLA2 Recombinant Protein Phospholipase A2(PLA2G1B) is a secreted protein which belongs to the phospholipase A2 family. It catalyzes the release of fatty acids from glycero-3-phosphocholines. It catalyzes the...

system_update_altDatasheetHuman PSPH Recombinant Protein Phosphoserine phosphatase (PSP) is an enzyme that belongs to the serB family. PSPH catalyzes magnesium-dependent hydrolysis of L-phosphoserine and is also involved in an exchange reaction between...

system_update_altDatasheetPMVK Recombinant Protein Phosphomevalonate kinase (PMVK) is a cytosolic enzyme. PMVK can be highly expressed in the heart,skeletal muscle, liver, pancreas, and kidney; it is expressed at lower levels in the brain, lung, and...