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GenieFluor 488 Anti-Mouse Ly6A/E (Sca-1) Antibody [D7] (AGEL2358)

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SKU:
AGEL2358
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Mouse
Host Species:
Rat
Isotype:
Rat IgG2a, κ
Clone:
D7
Conjugation:
AF488
$251 - $515

Description

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GenieFluor 488 Anti-Mouse Ly6A/E (Sca-1) Antibody [D7]

The GenieFluor 488 Anti-Mouse Ly6A/E (Sca-1) Antibody (D7) (AGEL2358) is a powerful tool for researchers studying stem cell biology and immune cell characterization. This antibody specifically targets Ly6A/E, also known as Sca-1, an important marker for stem cells and hematopoietic cells in mice. Developed with high specificity and sensitivity, the GenieFluor 488 Anti-Mouse Ly6A/E (Sca-1) Antibody (D7) allows for precise detection and analysis of Ly6A/E expression in various cell types and tissues. Its compatibility with fluorescence-based assays makes it ideal for flow cytometry and immunofluorescence applications.Ly6A/E, or Sca-1, is a key regulator of stem cell function and immune response modulation in mice.

Its expression is associated with stem cell populations, including hematopoietic stem cells and mesenchymal stem cells, making it a valuable marker for identifying and isolating these cell types in research settings. By understanding the role of Ly6A/E in stem cell biology and immune regulation, researchers can gain insights into developmental processes, tissue regeneration, and immune cell function. The GenieFluor 488 Anti-Mouse Ly6A/E (Sca-1) Antibody (D7) provides a reliable tool to explore these areas of study and advance scientific discovery in stem cell and immunology research.

Product Title:GenieFluor 488 Anti-Mouse Ly6A/E (Sca-1) Antibody [D7]
SKU:AGEL2358
Size:25µg, 100µg
Clone No:D7
Synonyms:Ly6a;Ly6;Ly-6A.2/Ly-6E.1;SCA-1;TAP;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:Genie Fluor 488 Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:Genie Fluor488
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P05533
Gene ID:110454
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:Ly-6A/E, also known as Sca-1, is an 18 kD member of the Ly-6 multigene family. Ly6A/E is a glycosylphosphatidylinositol (GPI)-linked protein expressed on hematopoietic stem cells. In mice expressing the Ly-6.2 haplotype (e.g., AKR, C57BL, C57BR, DBA/2, SJL, SWR, and 129), Ly-6A/E is also expressed on peripheral B lymphocytes and thymic and peripheral T lymphocytes. Strains expressing the Ly-6.1 haplotype (e.g., BALB/c, CBA, C3H/He, DBA/1, and NZB) have low Ly-6A/E expression on resting peripheral lymphocytes. The expression of Ly-6A/E on lymphocytes is upregulated upon activation from both Ly6.1 and Ly6.2 haplotype mice. Ly-6A/E is thought to be involved in the regulation of both T and B cell responses.

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