Description
| Product Name: | Nanodisc Human AGRB2 Protein |
| SKU: | HDFP185 |
| Size: | 10μg |
| Target: | AGRB2 |
| Tag: | C-Flag Tag |
| Expression Host: | HEK293 |
| Conjugate: | Unconjugated |
| Synonyms: | BAI2 |
| Protein Families: | Transmembrane, Druggable Genome. |
| Protein Description: | Human AGRB2 full length protein-synthetic nanodisc |
| Protein Pathways: | Angiogenesis, Apoptosis & Cell Cycle. |
| Molecular Weight: | The human full length AGRB2 protein has a MW of 172.7kDa |
This gene encodes a a seven-span transmembrane protein that is thought to be a member of the secretin receptor family. The encoded protein is a brain-specific inhibitor of angiogenesis. The mature peptide may be further cleaved into additional products (PMID:20367554). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]
| Uniprot ID: | O60241 |
| Formulation & Reconstitution: | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments. |
| Storage & Shipping: | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Usage: | Research use only |
