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Human FBLN4 / Fibrillarin ELISA Kit

SKU:
HUFI02446
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
P22087
Sensitivity:
0.938ng/ml
Range:
1.563-100ng/ml
ELISA Type:
Sandwich
Synonyms:
FBL
Reactivity:
Human
Research Area:
Epigenetics and Nuclear Signaling
$719
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Description

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Human FBLN4 / Fibrillarin ELISA

FBL (Fibrillarin) is a protein that is mainly expressed in the nerve cells of the central nervous system. Studies have shown that FBL plays a role in the biogenesis of small nuclear RNAs (snRNAs) and is required for the assembly of the spliceosome, which is responsible for snRNA processing. The loss of FBL activity has been linked to neurodegeneration, suggesting that this protein may be important for neuronal function. Diseases associated with FBL include Diffuse Scleroderma and Systemic Scleroderma. Among FBL related pathways are rRNA processing in the nucleus and cytosol and Cytoskeletal Signaling.