Description
| Product Name: | Nanodisc Human PAR1-Strep Protein |
| SKU: | HDFP1164 |
| Size: | 10μg |
| Target: | PAR1 |
| Tag: | C-Flag&Strep Tag |
| Expression Host: | HEK293 |
| Conjugate: | Unconjugated |
| Synonyms: | CF2R, HTR, PAR-1, PAR1, TR |
| Protein Families: | GPCR, Transmembrane, Druggable Genome. |
| Protein Description: | Human PAR1-Strep full length protein-synthetic nanodisc |
| Protein Pathways: | GPCRDB Class A Rhodopsin-like, GPCRDB Other, Regulation of Actin Cytoskeleton KEGG, Apoptosis, Cancer, Cell Cycle. |
| Molecular Weight: | The human full length PAR1-Strep protein has a MW of 47.4 kDa |
Coagulation factor II receptor is a 7-transmembrane receptor involved in the regulation of thrombotic response. Proteolytic cleavage leads to the activation of the receptor. F2R is a G-protein coupled receptor family member. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]
| Uniprot ID: | P25116 |
| Formulation & Reconstitution: | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments. |
| Storage & Shipping: | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Usage: | Research use only |
