APC Anti-Mouse CD117 Antibody [2B8] (AGEL1187)
- SKU:
- AGEL1187
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Mouse
- Applications:
- FC
![APC Anti-Mouse CD117 Antibody [2B8] (AGEL1187)](https://cdn11.bigcommerce.com/s-h68l9z2lnx/images/stencil/1280x1280/products/21718/606226/apc-anti-mouse-cd117-antibody-2b8-agel1187__25497.1707497348.jpg?c=2&imbypass=on "APC Anti-Mouse CD117 Antibody [2B8] (AGEL1187)")
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Description
| Product Title: | APC Anti-Mouse CD117 Antibody [2B8] |
| SKU: | AGEL1187 |
| Size: | 25µg, 100µg |
| Clone No: | 2B8 |
| Synonyms: | Mast/stem cell growth factor receptor Kit;Kit;SCFR;Proto-oncogene c-Kit;Tyrosine-protein kinase Kit;CD117; |
| Host Species: | Rat |
| Reactivity: | Mouse |
| Application: | FCM |
| Isotype: | Rat IgG2b, κ |
| Isotype Control: | APC Rat IgG2b, κ Isotype Control[LTF-2] |
| Form: | Liquid |
| Conjugation: | APC |
| Recommended Use: | Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume]. |
| Spectrum: |  |
| Swissprot: | P05532 |
| Gene ID: | 16590 |
| Storage Buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
| Stability & Storage: | Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase. |
| Background: | CD117 is a 145 kD immunoglobulin superfamily member also known as c-Kit and stem cell factor receptor (SCFR). It is a transmembrane tyrosine-kinase receptor that binds the c-Kit ligand (also known as steel factor, stem cell factor, and mast cell growth factor). CD117 is expressed on hematopoietic stem cells (including multipotent hematopoietic stem cells, progenitors committed to myeloid and/or erythroid lineages, and T and B cell precursors), mast cells, and acute myeloid leukemia (AML) cells. CD117 interaction with its ligand is critical for the development of hematopoietic stem cells. |
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