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Mouse HMGB1 ELISA Kit

SKU:
MOFI00232
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
P63158
Sensitivity:
9.375pg/ml
Range:
15.625-1000pg/ml
ELISA Type:
Sandwich ELISA, Double Antibody
Synonyms:
Hmgb1, HMG-1, Amphoterin, high mobility group box 1, High mobility group protein 1, high-mobility group, nonhistone chromosomal protein 1, high-mobility group box 1, HMG-1, HMG1DKFZp686A04236, HMG3, SBP-1, Sulfoglucuronyl carbohydRate binding protein
Reactivity:
Mouse
  • Mouse Immunology ELISA Kits Mouse HMGB1 ELISA Kit
  • Cong, X. et al., 2020. Cationic Liposome/DNA complexes mediate antitumor immunotherapy by promoting immunogenic tumor cell death and dendritic cell activation. ACS applied materials & interfaces, 12(25), pp.28047-28056.
  • Li, B. et al., 2021. HDAC5 promotes intestinal sepsis via the Ghrelin/E2F1/NF‐κB axis. The FASEB Journal, 35(7), p.e21368.
  • Tchekalarovaet al., 2022. The Anticonvulsant Effect of a Novel Indole-Related Compound in the Kainate-Induced Status Epilepticus in Mice: The Role of the Antioxidant and Anti-inflammatory Mechanism. Neurochemical Research, 47(2), pp.327-334.
  • Wang, Y et al., 2021. The Host‐Defense‐Peptide‐Mimicking Synthetic Polypeptides Effectively Enhance Antitumor Immunity through Promoting Immunogenic Tumor Cell Death. Macromolecular Bioscience, 21(9), p.2100171.
€599
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Description

Mouse HMGB1 ELISA Kit

HMGB1, a chromatin-binding protein and transcriptional regulator, acts as a damage associated molecular pattern (DAMP) when released extracellularly. It is a biomarker of inflammation, autoimmunity and cancers. The Assay Genie Mouse HMBG1 ELISA kit has been cited in various publications (view citations) whereby it is used as an indicator of active inflammation. It acts as a proinflammatory cytokine through binding to receptors TLR4 and RAGE and activating signaling pathways such as NF-κB and MAPK.

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Citations

Cong et al. Cationic Liposome/DNA Complexes Mediate Antitumor Immunotherapy by Promoting Immunogenic Tumor Cell Death and Dendritic Cell Activation ACS Appl Mater Interfaces. 12(25):28047-28056 (2020) PubMed: 32478501
Li et al. HDAC5 promotes intestinal sepsis via the Ghrelin/E2F1/NF-κB axis FASEB J. (2021) PubMed: 34125448
Tchekalarova et al. The Anticonvulsant Effect of a Novel Indole-Related Compound in the Kainate-Induced Status Epilepticus in Mice: The Role of the Antioxidant and Anti-inflammatory Mechanism Neurochem Res. (2021) PubMed: 34510375
Wang et al. The Host-Defense-Peptide-Mimicking Synthetic Polypeptides Effectively Enhance Antitumor Immunity through Promoting Immunogenic Tumor Cell Death Macromol Biosci. (2021) Pub Med: 34169661

Data from Citations

HMGB1 Data Released HMGB1 in culture supernatants measured with the Assay Genie HMGB1 ELISA (Cong et al.)
HMGB1 Data HMGB1 levels measured with the Assay Genie HMGB1 ELISA kit (Li et al.)
HMGB1 Data HMGB1 and RAGE values in hippocampus samples were quantified with mouse HMGB1 ELISA Kit and mouse AGER/RAGE ELISA Kit (Tchekalarova et al.)
HMGB1 Data Released HMGB1 in culture supernatants measured with the Assay Genie HMGB1 ELISA (Wang et al.)