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FITC Anti-Mouse MHC II (I-A/I-E) Antibody [M5/114] (AGEL0020)

SKU:
AGEL0020
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Host Species:
Rat
Isotype:
IgG2b
Clone:
M5/114
Conjugation:
FITC
Applications:
FC
€99 - €219
Frequently bought together:

Description

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FITC Anti-Mouse MHC II (I-A/I-E) Antibody [M5/114]

The FITC-Conjugated Mouse I-A/I-E Monoclonal Antibody (M5/114) is designed for advanced research involving I-A/I-E, pivotal molecules in the Major Histocompatibility Complex (MHC) class II system that are integral to antigen presentation and immune response activation. This monoclonal antibody, produced in mice, is highly reactive with mouse I-A/I-E and is validated for use in flow cytometry applications. The conjugation with fluorescein isothiocyanate (FITC) provides bright green fluorescence, enabling precise and reliable detection.I-A/I-E molecules are essential for the adaptive immune response, playing critical roles in presenting antigens to CD4+ T cells. Their significant function in immune regulation makes them valuable targets for research into diseases such as autoimmune disorders, chronic inflammatory conditions, and infectious diseases.

The FITC-Conjugated Mouse I-A/I-E Monoclonal Antibody (M5/114) is an indispensable tool for researchers aiming to dissect the mechanisms of antigen presentation and advance therapies that modulate immune function.By facilitating accurate and sensitive detection of I-A/I-E molecules, this antibody supports comprehensive studies of immune response pathways, contributing to the development of novel therapeutic strategies for autoimmune diseases and other immune-related conditions. Understanding the activity of I-A/I-E is crucial for the creation of innovative immunotherapies that harness or modulate antigen presentation in various disease states.

Product Title:FITC Anti-Mouse MHC II (I-A/I-E) Antibody [M5/114]
SKU:AGEL0020
Size:50 Tests, 100 Tests, 200 Tests
Clone No:M5/114
Synonyms:H2-Ab1/Eb1;Major histocompatibility protein class II beta chain;MHC class II H2-IA-beta-psi;I-E beta MHC class II;MHC class II;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:FITC Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:FITC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P14483 O78196
Gene ID:14961,14969
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:These class II molecules are expressed on antigen presenting cells (including B cells) and a subset of T cells from H-2b,d,q,r bearing mice and are involved in antigen presentation to T cells expressing CD3/TCR and CD4 proteins.

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