The Mouse MHC II (I-A/I-E) Monoclonal Antibody (APC-conjugated, M5/114) is a powerful tool for researchers interested in studying the major histocompatibility complex class II molecules in mouse models. This antibody, produced by Assay Genie, is specifically designed for flow cytometry applications, allowing for the identification and analysis of MHC II (I-A/I-E) expression on immune cells.MHC II molecules play a crucial role in antigen presentation and immune responses, making them key targets for investigation in immunology, vaccine development, and autoimmune disease research. The APC-conjugated M5/114 antibody offers high specificity and sensitivity, enabling precise detection of MHC II (I-A/I-E) molecules in various experimental settings.
By utilizing this monoclonal antibody, researchers can gain valuable insights into the regulation of antigen presentation and immune activation in mouse models. Whether studying T cell activation, immune system development, or the role of MHC II in disease pathogenesis, the Mouse MHC II (I-A/I-E) Monoclonal Antibody (APC-conjugated, M5/114) from Assay Genie provides a reliable tool for advancing scientific knowledge in the field of immunology.
Product Title:
APC Anti-Mouse MHC II (I-A/I-E) Antibody [M5/114]
SKU:
AGEL0501
Size:
25µg, 100µg
Clone No:
M5/114
Synonyms:
H2-Ab1/Eb1;Major histocompatibility protein class II beta chain;MHC class II H2-IA-beta-psi;I-E beta MHC class II;MHC class II;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2b, κ
Isotype Control:
APC Rat IgG2b, κ Isotype Control[LTF-2]
Form:
Liquid
Conjugation:
APC
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
P14483 O78196
Gene ID:
14961,14969
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
These class II molecules are expressed on antigen presenting cells (including B cells) and a subset of T cells from H-2b,d,q,r bearing mice and are involved in antigen presentation to T cells expressing CD3/TCR and CD4 proteins.
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