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Human CD47/IAP Recombinant Protein (RPES5234)

SKU:
RPES5234
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Cell Biology
€511
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Description

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Human CD47/IAP Recombinant Protein

CD47(Integrin-Associated Protein;IAP) is a 40 - 60 kDa variably glycosylated atypical member of the immunoglobulin superfamily. The ubiquitously expressed CD47 binds to SIRP family members on macrophages; neutrophils; and T cells. CD47 is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The protein is also a receptor for the C-terminal cell-binding domain of thrombospondin; and it may play a role in membrane transport and signal transduction. This protein has broad tissue distribution; and is reduced in expression on Rh erythrocytes.