null

Human TNFRSF1B/CD120b Recombinant Protein (RPES1604)

SKU:
RPES1604
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Growth Factors & Cytokines
$283
Frequently bought together:

Description

system_update_altDatasheet

Human TNFRSF1B/CD120b Recombinant Protein

Tumor necrosis factor receptor superfamily member 1B(TNFRSF1B) is expressed by the gene TNFRSF1B. The soluble form is produced from the membrane form by proteolytic processing. It can bind to TRAF2; and interacts with BMX. It can act as the receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha.