4870 results for 'rel'

Quick Facts About RelatlimabWhat is Relatlimab?Relatlimab is a monoclonal antibody that targets LAG-3 (Lymphocyte Activation Gene-3), a key immune checkpoint involved in T-cell regulati ...

Since I am from Ireland I thought I would give as comprehensive view as possible for Research Universities in Ireland. By now you are probably considering looking for a PhD or PostDoc posit ...

After probably a round or two of interviews and a PhD in your pocket you would think that proving yourself in your new lab would not be an issue. After all, they did hire you because you were ...

Quick Facts About VixarelimabWhat is Vixarelimab?Vixarelimab is an investigational monoclonal antibody developed to target oncostatin M receptor beta (OSMRβ), a key pathway involved in ...

Treponema pallidum, the causative agent of syphilis, triggers an immune response that produces antibodies detectable by laboratory tests. Diagnosing syphilis often involves detecting the ...

Understanding the Bcl-2 Pathway: Implications for Cancer Therapy The Bcl-2 family of proteins plays a pivotal role in regulating apoptosis, a crucial process for maintaining cellula ...

What does the COVID-19 Rapid POC CE-IVD Test detect? The test detects the presence of patient-generated antibodies against spike protein, the virus which causes the disease COVID-19. The te ...

What is Parkinson’s disease? Parkinson's disease can be seen as a neurodegenerative disease because it is associated with the loss of nerve ce ...

The choice of appropriate cell culture supplements emerges as a crucial factor in ensuring the efficacy and consistency of experimental results. Among the various options available, two common ...

Sarah Brun Bar-Yaacov PhD Candidate, University of Liverpool Orthohantaviruses are a group of segmented negative-sense RNA viruses maintained as asympt ...

Delve into the world of C-reactive protein (CRP), a critical player in the body's response to inflammation, and understand its role in health and disease. Key Takeaways C-reacti ...

Monocytes, as part of the innate immune system, act as the first line of defense against foreign invaders. One of their primary functions is phagocytosis, a crucial process in which they engul ...

Interferons (IFNs) are a group of signalling proteins that are produced and released from cells in response to viral infection and other stimuli such as normal and tumour cell survival and ...

The recent advances in cancer immunotherapy have brought new opportunities to harness the body’s immune system against tumors. Among these advancements is the targeting of immune checkpo ...

What are Stem Cells? Stem cells are primitive, undifferentiated, and unspecialised cells that are found in multicellular organism ...

By Dr. Niclas Thomas “Data science” is a recent addition to the vocabulary of analytics, and can mean many different things to different people. As f ...

By Charlotte O'Donnell PhD ...

Fluorescence Resonance Energy Transfer (FRET) assays represent a pivotal technique in the molecular and cellular biology fields, enabling the examination of protein interactions, nucleic acid str ...

Alex Lloyd PhD Candidate, Dublin Institute of Technology Did you know that roughly 17.5 million people worldwide die annually from Cardiovascular disease ...

Mouse monoclonal antibodies are a valuable tool in the biomedical field. They can be used for a variety of applications, from research to clinical diagnostics. In this blog post, we ...

The angiotensin pathway is a pivotal hormonal system that plays a crucial role in regulating blood pressure and maintaining fluid and electrolyte balance within the body. This complex biochemical ...

Alzheimer's disease stands as a formidable challenge in the realm of neurological disorders, characterized by its progressive nature and profound impact on cognitive functions. This article delv ...

In the realm of molecular biology and genetic engineering, the ability to deliver genetic material into cells is fundamental for various research and therapeutic purposes. Two common methods e ...

In this blog post, we will review prostate cancer markers and what you should look for in your results. Prostate antigen marker (PSA) and p63 are the most common markers found in pr ...

By Eleni Chrysostomou, PhD Candidate, NUIG Why do we need to know how the Nervous System develops and regenerates? The structure and function of ...

T Cell Types, Activation, Polarization & Function A comprehensive guide to T cells! window.SHOGUN_IMAGE_ELEMENTS = window.SHOGUN_IMAGE_ELEMENTS || new Array(); wi ...

Both Assay Genie MORV0010 and Promega E1910 effectively quenched Firefly luciferase before Renilla detection, minimizing signal overlap. E1910 achieved 99.95% quenching efficiency, whil ...

Centrifuges play a pivotal role in scientific research and various industries, enabling efficient separation and isolation of components within a sample. Understanding the relations ...

Overview: Doublet discrimination is essential in Fluorescence-Activated Cell Sorting (FACS) to ensure accurate results, as doublets (two cells sticking together) can resemble single cell ...

Non-Small Cell Lung Carcinoma (NSCLC) is the most common type of lung cancer, representing about 85% of all lung cancer cases. NSCLC includes several subtypes, with distinct biological c ...

Seroconversion Implications in SARS-CoV-2 Diagnostic Testing Key Points: COVID-19, the pandemi ...

I have been in the situation that I’m sure many of us have. I work on genes, which if you name to any right-minded individual, sound like a random string of nonsensical gibberish. So, mayb ...

What is Cortisol? Cortisol is a steroid hormone, classified as a member of the glucocorticoid family of hormones. Cortisol is involved in a plethora of physiological processes in order ...

Glycolysis is a fundamental metabolic pathway that involves the breakdown of glucose to produce energy. This process can occur through two main pathways: aerobic and anaerobic glycolysis. Both p ...

Nod-like receptors Nod like receptors (NLRs) are a versatile family of relatively recently discovered intracellular receptors which have a b ...

Quick Facts About BegelomabWhat is Begelomab?Begelomab is a monoclonal antibody that targets CD26, a key molecule involved in immune regulation. It has been studied for its potential ap ...

Introduction Phosphorylation is a fundamental biochemical process that plays a crucial role in various cellular functions. It involves the addition of a phosphate group to a molecule, typ ...

Quick Facts About PraluzatamabWhat is Praluzatamab?Praluzatamab is an experimental monoclonal antibody that targets CD47, a “don’t eat me” signal used by cancer cells to evade immune de ...

Schwann cells are cells that play a vital role in nerve function. They are responsible for myelinating axons and helping to ensure the transmission of electrical signals between neurons. Schwann ...

Imagine a microscopic sniper, capable of delivering a lethal blow to a single cancer cell while leaving its healthy neighbors virtually untouched. This is the promise of targeted alpha therapy, a re ...

Platelets, the tiny cellular fragments found in our blood, play a crucial role in maintaining our overall health and well-being. From their role in blood clotting to their involveme ...

By Ciara Coleman PhD General Introduction Coeliac Disease (CD) is defined as a common, chronic inflammatory di ...

What is a Macrophage? Macrophages are indeed a type of phagocyte, responsible for engulfing and destroying foreign particles and cellular debris. They are larger cells with more cytoplasm a ...

By Charlotte O’Donnell PhD Cancer Carcinogenesis is a multi-step process that develops through epigenetic changes an ...

Key Takeaways: Microglia are immune cells in the CNS, originating from myeloid precursor cells. They surveil the CNS, respond to changes, and maintain neural health. Microglia exist in dif ...

Apoptosis Unveiled: Your Complete Guide to Intrinsic & Extrinsic PathwaysAt Assay Genie we have created a comprehensive guide outlining everything you need to know about apoptosis!K ...

Overview of Diabetes Mellitus Diabetes mellitus (DM) is a major epidemic that affects over 347 million people worldwide (Danaei et al. 2011). The World He ...

At Assay Genie we have created a comprehensive guide outlining everything you need to know about apoptosis! Key Takeaways: Apoptosis is a programmed cell death process, vital for tissu ...

Exploring IL-18: A key cytokine in inflammation and disease. Key Takeaways: IL-18, a pro-inflammatory cytokine, plays a pivotal role in immune responses, particularly in inducing Type II ...

Mononuclear phagocytes, essential in immunity and homeostasis, perform diverse roles from phagocytosis to tissue repair, influencing health and disease. Key Takeaways: Mononuclear ...

Imagine engineering a patient's own immune cells into precision-guided missiles against cancer—cells that can seek out and destroy tumors with remarkable specificity. This is the promise of CAR-T cel ...

Toll-Like Receptors The innate immune response has come under the spotlight in recent years due to its central role in propagating the pathoge ...

Cell-Based ELISA Kits No More Western Blots! Over 1,600 Cell-Based ELISA kits to measure the relative levels of intracellular and phosphorylat ...

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COVID-19 Rapid Tests What is COVID-19? SARS-CoV-2 is the causative viral agent of the disease COVID-19. It is primarily transmitt ...

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What is Subcellular Fractionation? Subcellular fractionation is the process of iIsolating nuclear, cytosolic and mitochondrial fractions of high purity from tissues. Subcellular fracti ...

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