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10181 results for 'replac name p65'

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    Interferons(Post)

    Interferons (IFNs) are a group of signalling proteins that are produced and released from cells in response to viral infection and other stimuli such as normal and tumour cell survival and ...

    ST2 and IL33(Post)

    ST2, a member of the IL-1R Subfamily ST2 is a member of the IL-1R subfamily and was identified in 1989 [1]. The ST2 gene is located on chromos ...

    NLRP3 Inflammasome & Cytokine Secretion(Post)

    Nod-like receptors Nod like receptors (NLRs) are a versatile family of relatively recently discovered intracellular receptors which have a b ...

    PCR Detection of COVID-19 (SARS-CoV-2)(Post)

    PCR Detection of COVID-19 (SARS-CoV-2) Contents Background Assay Information Sample Types   & ...

    Tocilizumab (Actemra®) in COVID-19 Treatment(Post)

    Tocilizumab (Actemra®) in COVID-19 Treatment What is Tocilizumab? Tocilizumab, also called atlizumab, is an immunosuppres ...

    Immunometabolism – A therapeutic perspective(Post)

    What is Immunometabolism? Immunometabolism is an exponentially growing, multi-disciplinary field of research aiming at deciphering the dynamic cellular and mol ...

    miRNAs as therapeutics and biomarkers for pancreatic cancer(Post)

    Pancreatic cancer survival rates Despite recent advances in our understanding of this disease, pancreatic cancer is one of the world’s most lethal maligna ...

    The Exciting Field of Stem Cell Research(Post)

    What are Stem Cells? Stem cells are primitive, undifferentiated, and unspecialised cells that are found in multicellular organism ...

    The Role of ACE2 in SARS-CoV-2(Post)

    Structure, Function, and Detection Assays for COVID-2019 Background The global spread of the novel co ...

    The Role of Tumor Suppressor Genes in Cancer: Knudson Hypothesis & Oncogenes(Post)

    The focus of this article is Tumor Suppressor Genes. There are various different types of tumor suppressor genes, with BRCA being one of the most popular. The role of Tumor Suppressor Genes in Ca ...

    Human Papilloma Virus (HPV) Methylation Analysis(Post)

    Stephen Reynolds, PhD Student, CERVIVA and Trinity College Dublin We hear almost daily now how everyone in their lifetime will be touched by cancer either directly or through a close f ...

    Passaging Hybridoma Cells: A Detailed Guide(Post)

    Hybridoma cells are essential tools for producing monoclonal antibodies and are derived by fusing B lymphocytes (antibody-producing cells) with myeloma cells (cancer cells) to achieve bo ...

    Immuno-Biomaterial Development | Assay Genie(Post)

    Background I am a 3rd year PhD student in Trinity College Dublin and my project is very much an interdisciplinary one. I’m very lucky to get to work between two great labs, Dr. Aisling Dun ...

    Leukemia Inhibitory Factor: An Overview (Post)

    Leukemia Inhibitory Factor and JAK-STAT Signalling Pathway Leukemia inhibitory factor (LIF) is a cytokine that belongs to the interleukin-6 (IL-6) family of cytokines. Other members of ...

    Treponema pallidum Antibodies: Comprehensive Guide to Diagnostic and Clinical Relevance(Post)

    Treponema pallidum, the causative agent of syphilis, triggers an immune response that produces antibodies detectable by laboratory tests. Diagnosing syphilis often involves detecting the ...

    Novel Gene Therapy for Cystic Fibrosis (Post)

    Novel Gene Therapies for Cystic Fibrosis Cystic Fibrosis Cystic fibrosis (CF) is an autosomal recessive, life-limiting disease resulting from gene mutations that encode the cystic fib ...

    Belimumab: Unveiling Its Role in Lupus and Beyond(Post)

    Quick Facts About BelimumabWhat is Belimumab?Belimumab is a monoclonal antibody used to treat systemic lupus erythematosus (SLE), an autoimmune disease. It is marketed under the brand n ...

    Spanish Flu: The Deadliest Pandemic in History(Post)

    The Spanish flu pandemic of 1918-1919 was the deadliest in history. It is estimated that up to 100 million people died from the virus, which is more than three times the number who ...

    Hydroxychloroquine: Potential Treatment for COVID-19(Post)

    Hydroxychloroquine: Potential Treatment for COVID-19 What is Hydroxychloroquine? Hydroxychloroquine (HC ...

    Polyclonal Vs Monoclonal antibodies: Key features (Post)

    In the field of immunology and biomedical research, antibodies play a crucial role in identifying and targeting foreign substances in the body. However, not all antibodies are the same. In this b ...

    Amatuximab: Exploring Mesothelin-Targeted Therapy for Cancer Research(Post)

    What You Need to Know About AmatuximabIs Amatuximab safe?Amatuximab has shown a manageable safety profile in clinical trials, with most side effects being mild to moderate. Severe adver ...

    Validation of MycoGenie Rapid Mycoplasma Detection Kit - A highly sensitive visual determination method for Mycoplasma detection.(Post)

    The MycoGenie Rapid Mycoplasma Detection Kit enables the detection of 28 Mycoplasma species in under 1 hour using a simple visual determination method, eliminating the need for expensiv ...

    Phosphorothioate: Enhancing Stability in Oligonucleotide-Based Therapies(Post)

    Phosphorothioate is a chemical modification commonly used in oligonucleotide-based therapies to enhance the stability and efficacy of therapeutic nucleic acids. In this modification, one ...

    Sci-Hub: Your Proxy to Unrestricted Knowledge(Post)

    Introduction to Sci-Hub In the realm of science and academia, one name has been echoing in every corner of the globe, Sci-Hub. Created by Alexandra Elbakyan, a Kazakhstani computer scientis ...

    Polo-like kinase (Plk1) substrates and mitosis(Post)

    Polo-like kinase (Plk1) Polo-like kinase (Plk1), is a serine/threonine kinase that is active during mitosis (Hamanaka et al., 1995). Its name is derived from its orig ...

    Innate Viral Immunity & RIG-I in COVID-19(Post)

    RIG-I: Antiviral Properties in COVID-19 (SARS-CoV-2) Infection Key Points RIG-I is a cytosolic RNA ...

    Polatuzumab: Redefining Targeted Therapies in B-Cell Lymphoma(Post)

    What You Need to Know About PolatuzumabWhat is Polatuzumab??Polatuzumab vedotin is an antibody-drug conjugate targeting CD79b, a component of the B-cell receptor, used primarily in B-ce ...

    How do different types of vaccines work? (Post)

    What is a vaccine? A vaccine is a pharmacological product that gives the recieving patient's immune system a chance to learn how to fight infection with decreased risk of illness. Vacc ...

    Rapid COVID Antibody Test | Antibody Tests(Post)

    What does the COVID-19 Rapid POC CE-IVD Test detect? The test detects the presence of patient-generated antibodies against spike protein, the virus which causes the disease COVID-19. The te ...

    Networking tips for scientists(Post)

    During my PhD I knew how networking was important, it helped me source reagents off other labs, get the best advice and helped me land a post doc at Cambridge University. Its not ...

    Build a science blog to progress your career(Post)

    What do scientists consider their skill set when looking for jobs outside of academia? Mine where hard to sum. I was a PhD in cell biology. I could Western Blot, I had used thousands of ant ...

    TLX as a Novel Therapeutic Target(Post)

    Danka Kozareva PhD Candidate, University College Cork The generation of neurons from stem cells The process of generating ...

    Inhibiting cell division(Post)

    Unregulated cell growthCancer, although heterogeneous by its very nature, can be broadly defined as a set of diseases characterised by unregulated cell growth leading to invasion of surroundin ...

    Early Diagnosis is key: Pick the weed or allow it destroy the garden?(Post)

    By Catríona Dowling, Post-Doc, RCSI I want you to come on a journey with me where we are going to the botanic gardens. You will pick a section of the garden that is yours: yours to treasure ...

    STING Activators As Cancer Therapeutics(Post)

    The STING (Stimulator of Interferon Genes) pathway plays a pivotal role in the innate immune system's response to cancerous cells and DNA viruses. Exploiting this pathway through STING activators ...

    COVID-19 Workplace Testing(Post)

    Workplace Testing for COVID-19 Corporate Testing for COVID-19 The impact of COVID-19 on the econo ...

    Prostate Cancer Markers : What to Look for in Your Test Results(Post)

    In this blog post, we will review prostate cancer markers and what you should look for in your results. Prostate antigen marker (PSA) and p63 are the most common markers found in pr ...

    COVID-19 Vaccine Candidates(Post)

    What is COVID-19 COVID-19, the disease caused by the coronavirus named SARS-CoV-2, first identified in Wuhan, China in December 2019 has spr ...

    Mononuclear Phagocytes in Health and Disease(Post)

    Mononuclear phagocytes, essential in immunity and homeostasis, perform diverse roles from phagocytosis to tissue repair, influencing health and disease. Key Takeaways: Mononuclear ...

    Bone Resorption Explained: Process, Markers, and Clinical Insights(Post)

    Bone Resorption Explained: Process, Markers, and Clinical InsightsUnravel the complexities of bone resorption, a crucial biological process essential for skeletal health and calcium reg ...

    Phosphatases and PTP1B – Mini review(Post)

    IntroductionThe human kinome is estimated to contain 518 genes, in comparison to the estimated 180 genes that comprise the phosphatome (Arena et al., 2005). These kinase genes represent a signi ...

    Mesenchymal Stem Cells: Navigating the Frontiers of Regenerative Medicine(Post)

    Mesenchymal stem cells (MSCs) have emerged as pivotal players in the realm of regenerative medicine due to their unique properties and versatile potential. Originally discovered in the bone marro ...

    Clinical Pathology Labs List: Overview, Services, and Importance(Post)

    Clinical pathology labs play a crucial role in modern healthcare, providing critical diagnostic testing services for a wide array of diseases and conditions. These laboratories are desig ...

    Targeting Immune Checkpoints as Cancer Therapy(Post)

    The advent of immune checkpoint targeting marks a significant milestone in the oncological field, offering a beacon of hope for patients battling cancer. This innovative approach leverages the bo ...

    TNF cytokines and their Receptors(Post)

    The human body is a complex and intricate system where various components work together to maintain health and combat potential threats. Among these essential players are the TNF cy ...

    Tau proteins: An Overview (Post)

    The tau protein is a hot topic in the scientific world right now. This little-known protein has been linked to Alzheimer's disease, Parkinson's disease, and other neurodegenerative dise ...

    Pyroptosis: A Promising Target for Immunotherapy(Post)

    Pyroptosis is an immunogenic form of cell death, meaning that it triggers an immune response. This makes pyroptosis a potentially promising target for immunotherapies that aim to bo ...

    Cell Synchronisation Methods(Post)

    What is Cell Synchronisation? Cell synchronisation is a process by which cells at different stages of the cell cycle in a culture are brought to the same phase. Cell synchronisation is ...

    Protease vs Peptidase: Understanding Enzymatic Digestion(Post)

    In the complex world of biochemical processes, enzymes play a crucial role in catalyzing various reactions necessary for life. Among these enzymes, proteases and peptidases are fundamental pla ...

    CV writing tips for scientists(Post)

    Making the switch! This article provides some help on CV writing tips for scientists for PhDs and PostDocs looking for jobs outside of academia and what they might need to ...

    Bone Resorption: Process, Markers & Clinical Significance(Post)

    Unravel the complexities of bone resorption, a crucial biological process essential for skeletal health and calcium regulation, through the intricate roles of osteoclasts and osteoblasts. K ...

    M2 Supplement for Organoid Cell Culture: Enhancing Growth and Differentiation(Post)

    The use of M2 Supplement in organoid culture has revolutionized the way researchers cultivate and maintain these three-dimensional (3D) cellular models. Organoids—self-organizing cell cl ...

    The double-edged sword in prostate cancer therapy(Post)

    By Zoe Angel, PhD Student, Ulster University Prostate cancer is now the commonest cancer in men and it is the fifth leading cause of death (1). Researc ...

    Etigilimab: Unveiling the Role of Anti-TIGIT in Cancer Research(Post)

    Key Facts About EtigilimabWhat is Etigilimab?Etigilimab is an anti-TIGIT monoclonal antibody being studied for its potential role in cancer immunotherapy.What role does Etigilimab play ...

    Esophageal Cancer: Causes, Symptoms, Diagnosis, Treatment, and Prevention(Post)

    Esophageal cancer is a type of cancer that affects the esophagus, which is the tube that carries food and liquids from your mouth to your stomach. Esophageal cancer can cause many d ...

    Transcription Factor Activity Assay Kits(Page)

    Transcription Factor Assays Detect Transcription Factors via indirect ELISA methods! Detect transcription factors or study transcription fact ...

    SARS-CoV-2 Host Cell Proteases(Page)

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    High-Fidelity DNA Polymerase(Page)

    What is DNA Polymerase Fidelity? The fidelity of a DNA polymerase is the result of accurate replication of a desired template. The fidelity of DNA polymerase ...

    Citations(Page)

    Product CitationsMore than 1,000 cited products in scientific journalsWe're not just any scientific company; our products have made waves in the scientific community. From groundbreakin ...

    Arrays (Page)

    Antibody Arrays Detect 7-274 proteins in 10 species! Perfect for biomarker discovery and validation studies! Browse by Research Area ...

    Quick Test Strips & Other Reagents(Page)

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    ACE2 Assays(Page)

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    ELISA Sampler Packs(Page)

    ELISA Sampler Packs Based on thousands of citations and years of scientific endeavour, Assay Genie has developed ELISA Sampler Packs. An ELISA Sampler Pack is a ...

    Top 10 Therapeutics(Page)

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    COVID-19 Cytokine Storm Multiplex Assays(Page)

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    Urea Assays(Page)

    Urea Assays At Assay Genie we've developed a range of Urea assays for researchers to analyse key steps in the Urea Pathway.

    Site Directed Mutagenesis(Page)

    Key Takeaways: Site-directed mutagenesis (SDM) enables precise DNA sequence alterations. Used for investigating protein activity changes and introducing beneficial mutations. GenieClone ki ...

    SARS-CoV-2 ELISA Kits(Page)

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    Rat Multiplex ELISA Panels(Page)

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    Pre-clinical & Large Animal Antibodies(Page)

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    Oxidative Stress Assays(Page)

    Oxidative Stress Assays Simple & Sensitive Assays to Investigate Oxidative Stress! ...

    Liver & Kidney Biomarker Assays(Page)

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    Anti-Tag Antibodies(Page)

    Anti-Tag Antibodies Highly Specific and Non-reactive Anti-Tag Antibodies Explore Anti-Tag Antibodies window.SHOGUN_IMAGE_ELEMENTS = window ...

    Non-Human Primate Multiplex ELISA Panels(Page)

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    Apoptosis Assays(Page)

    Assay Genie has developed an extensive suite of assays to measure various forms of cell death. We provide highly sensitive & reprod ...

    ChIP Antibodies(Page)

    ChIP Antibodies Highly Validated ChIP Antibodies Organised by Epigenetic Modifications! window.SHOGUN_IMAGE_ELEMENTS = window.SHOGUN_IMAGE_ELEMENTS || new Arra ...

    TCA Cycle Assays(Page)

    TCA/Krebs Cycle Assays At Assay Genie we've developed a range of TCA assays for researchers to analyse key steps in the Krebs/TCA/Citric Acid cycle pathway. Different Products ...

    High Sensitivity Cytokine ELISA Kits & Multiplex Panels(Page)

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    Disease and Pathways Tools(Page)

    Disease & Pathway ToolsEmpower you Biomedical ResearchDiscover high-quality tools for studying disease pathways, biomarker discovery, and therapeutic development. Ideal for immunolo ...

    Localised Resources(Page)

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    Mouse Multiplex Inflammation ELISA Panels(Page)

    The ELISA Genie, Mouse inflammation multiplex assays utilizes multiple bead populations differentiated by size and different levels of fluorescence intensity. With multiple sizes of bea ...

    Protocols(Page)

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    Cation and Inorganic Ion Assays(Page)

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    Tunel 1-Step Assay Kits(Page)

    1-Step TUNEL Kits Unique 1-Step Non-Toxic Dewaxing Step for Late Stage Apoptosis Detection Explore TUNEL Assays ...

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    Mycoplasma Testing - Detection & Elimination(Page)

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    Amino Acid and Protein Assays(Page)

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    Glycolysis & Carbohydrates Assay Kits(Page)

    Glycolysis & Carbohydrates Assays At Assay Genie we've developed a range of Glycolysis & Carbohydrates assays for researchers to analyse key indicators in the glycolysis pathwa ...

    Ferroptosis Assays(Page)

    At Assay Genie we've developed a range of Cell Death & Ferroptosis assays for researchers to analyse key steps in the Ferroptosis pathway.

    DNA Ligation(Page)

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    SARS-CoV-2 Strains(Page)

    COVID-19 COVID-19, the newest coronavirus to gain international attention, is caused by severe acute respiratory syndrome coronavirus 2. The most common abbrev ...

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    Annexin V Assays(Page)

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    Recombinant Proteins for SARS-CoV-2 Research(Page)

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    Lipid Metabolism Assays(Page)

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    Human Multiplex ELISA Panels(Page)

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    Human Multiplex Inflammation ELISA Panels(Page)

    The ELISA Genie, Human Inflammation multiplex assays utilizes multiple bead populations differentiated by size and different levels of fluorescence intensity. With multiple sizes of bea ...

    Mouse Multiplex ELISA Panels(Page)

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