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Anti-Musashi-1 (MSI1) Antibody (CAB9122)

SKU:
CAB9122
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
MSI1
musashi RNA binding protein 1
Research Area:
Cell Biology
$167 - $503
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Description

Product Name:Musashi-1 (MSI1) Rabbit mAb
Product Code:CAB9122
Size:20uL, 50uL, 100uL
Synonyms:MSI1, musashi RNA binding protein 1
Applications:WB, IF
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:A synthesized peptide derived from human Musashi-1 (MSI1)
Applications:WB, IF
Recommended Dilutions:WB 1:500 - 1:2000 IF 1:50 - 1:200
Reactivity:Human, Mouse
Positive Samples:SH-SY5Y, Mouse brain
Immunogen:A synthesized peptide derived from human Musashi-1 (MSI1)
Purification Method:Affinity purification
Storage:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:4440
Uniprot:O43347
Cellular Location:Cytoplasm, Nucleus
Calculated MW:39kDa
Observed MW:39kDa
UniProt Protein Function:Musashi-1: RNA binding protein that regulates the expression of target mRNAs at the translation level. Regulates expression of the NOTCH1 antagonist NUMB. Binds RNA containing the sequence 5'- GUUAGUUAGUUAGUU-3' and other sequences containing the pattern 5'- [GA]U(1-3)AGU-3'. May play a role in the proliferation and maintenance of stem cells in the central nervous system. Detected in fetal kidney, brain, liver and lung, and in adult brain and pancreas. Detected in hepatoma cell lines. Belongs to the Musashi family.
UniProt Protein Details:

Protein type:RNA-binding

Chromosomal Location of Human Ortholog: 12q24

Molecular Function:RNA binding

Biological Process: nervous system development

NCBI Summary:This gene encodes a protein containing two conserved tandem RNA recognition motifs. Similar proteins in other species function as RNA-binding proteins and play central roles in posttranscriptional gene regulation. Expression of this gene has been correlated with the grade of the malignancy and proliferative activity in gliomas and melanomas. A pseudogene for this gene is located on chromosome 11q13. [provided by RefSeq, Jul 2008]
UniProt Code:O43347
NCBI GenInfo Identifier:51316193
NCBI Gene ID:4440
NCBI Accession:O43347.1
UniProt Secondary Accession:O43347,Q96PU0, Q96PU1, Q96PU2, Q96PU3,
UniProt Related Accession:O43347
Molecular Weight:39,125 Da
NCBI Full Name:RNA-binding protein Musashi homolog 1
NCBI Synonym Full Names:musashi RNA binding protein 1
NCBI Official Symbol:MSI1  
NCBI Protein Information:RNA-binding protein Musashi homolog 1
UniProt Protein Name:RNA-binding protein Musashi homolog 1
Protein Family:RNA-binding protein
UniProt Gene Name:MSI1  
UniProt Entry Name:MSI1H_HUMAN

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