Anti-Phospho-TDP-43/TARDB-S409/S410 Antibody

Product Name:	Phospho-TDP-43/TARDB-S409/S410 Rabbit pAb
Product Code:	CABP1241
Size:	50uL, 100uL
Synonyms:	ALS10, TDP-43, TARDBP, TDP43
Applications:	WB
Reactivity:	Human
Host Species:	Rabbit
Immunogen:	A phospho synthetic peptide corresponding to residues surrounding S409/S410 of Human TDP-43/TARDB.

Immunogen:	A phospho synthetic peptide corresponding to residues surrounding S409/S410 of Human TDP-43/TARDB.
Purification Method:	Affinity purification
Storage:	Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:	IgG
Sequence:	MSEY IRVT EDEN DEPI EIPS EDDG TVLL STVT AQFP GACG LRYR NPVS QCMR GVRL VEGI LHAP DAGW GNLV YVVN YPKD NKRK MDET DASS AVKV KRAV QKTS DLIV LGLP WKTT EQDL KEYF STFG EVLM VQVK KDLK TGHS KGFG FVRF TEYE TQVK VMSQ RHMI DGRW CDCK LPNS KQSQ DEPL RSRK VFVG RCTE DMTE DELR EFFS QYGD VMDV FIPK PFRA FAFV TFAD DQIA QSLC GEDL IIKG ISVH ISNA
Gene ID:	23435
Uniprot:	Q13148
Cellular Location:	Nucleus
Calculated MW:	31kDa/44kDa
Observed MW:	Refer to figures

NCBI Summary:	HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20. [provided by RefSeq, Jul 2008]
UniProt Code:	Q13148
NCBI GenInfo Identifier:	20140568
NCBI Gene ID:	23435
NCBI Accession:
UniProt Related Accession:	Q13148
Molecular Weight:	44
NCBI Full Name:	TAR DNA-binding protein 43
NCBI Synonym Full Names:	TAR DNA binding protein
NCBI Official Symbol:	TARDBP
NCBI Official Synonym Symbols:	ALS10; TDP-43
NCBI Protein Information:	TAR DNA-binding protein 43
UniProt Protein Name:
UniProt Gene Name:

Illuminating the Multifaceted Role of Acetylation: Bridging Chemistry and Biology Introduction: