[KO Validated] M6PR Rabbit Polyclonal Antibody (CAB19907)
- SKU:
- CAB19907
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Signal Transduction
Frequently bought together:
Description
Product Name: | [KO Validated] M6PR Rabbit Polyclonal Antibody |
SKU: | CAB19907 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 27-185 of human M6PR (NP_002346.1). |
Sequence: | TEEK TCDL VGEK GKES EKEL ALVK RLKP LFNK SFES TVGQ GSDT YIYI FRVC REAG NHTS GAGL VQIN KSNG KETV VGRL NETH IFNG SNWI MLIY KGGD EYDN HCGK EQRR AVVM ISCN RHTL ADNF NPVS EERG KVQD CFYL FEMD SSLA CSPE ISH |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | SMPR; MPR46; CD-MPR; MPR 46; MPR-46; CD-M6PR; PR |
Positive Sample: | 293T |
Conjugate: | Unconjugated |
Cellular Localization: | Lysosome membrane, Single-pass type I membrane protein. |
Calculated MW: | 31kDa |
Observed MW: | 31kDa |
This gene encodes a member of the P-type lectin family. P-type lectins play a critical role in lysosome function through the specific transport of mannose-6-phosphate-containing acid hydrolases from the Golgi complex to lysosomes. The encoded protein functions as a homodimer and requires divalent cations for ligand binding. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome X.
Purification Method: | Affinity purification |
Gene ID: | 4074 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |