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Human IDH1 Recombinant Protein (RPES2687)

SKU:
RPES2687
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Metabolism
$428
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Description

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Human IDH1 Recombinant Protein

Isocitrate Dehydrogenase [NADP] Cytoplasmic (IDH1) belongs to the isocitrate and isopropylmalate dehydrogenases family. IDH1 exists as a homodimer; binding one magnesium or manganese ion per subunit. Mutations of IDH1 have been shown to cause metaphyseal chondromatosis with aciduria and are involved in the development of glioma IDH plays a role in the regeneration of NADPH for intraperoxisomal reductions; such as the conversion of 2; 4-dienoyl-CoAs to 3-enoyl-CoAs; as well as in peroxisomal reactions that consume 2-oxoglutarate; namely the ?-hydroxylation of phytanic acid.