The RXFP1 Polyclonal Antibody (CAB7127) is a valuable tool for researchers studying RXFP1, a G protein-coupled receptor involved in various physiological processes, such as reproduction and cardiovascular regulation. This antibody, produced in rabbits, exhibits high specificity for human samples and is validated for use in Western blot applications. By binding to the RXFP1 protein, it allows for precise detection and analysis in a variety of cell types, making it an essential reagent for studies in endocrinology, reproductive biology, and cardiovascular research.RXFP1's role as a receptor for relaxin hormones highlights its importance in reproductive health, particularly in processes such as ovulation, implantation, and pregnancy.
Additionally, its involvement in cardiovascular functions, such as blood pressure regulation and vascular remodeling, underscores its significance in cardiovascular research and potential therapeutic interventions for cardiovascular diseases.By utilizing the RXFP1 Polyclonal Antibody, researchers can gain insights into the mechanisms underlying reproductive and cardiovascular physiology, leading to a better understanding of related disorders and the development of novel therapeutic strategies targeting the RXFP1 pathway.
Product Name:
RXFP1 Rabbit Polyclonal Antibody
SKU:
CAB7127
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 673-757 of human RXFP1 (NP_067647.2).
This gene encodes a member of the leucine-rich repeat-containing subgroup of the G protein-coupled 7-transmembrane receptor superfamily. The encoded protein plays a critical role in sperm motility, pregnancy and parturition as a receptor for the protein hormone relaxin. Decreased expression of this gene may play a role in endometriosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Purification Method:
Affinity purification
Gene ID:
59350
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using RXFP1 Rabbit pAb (CAB7127) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
