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TBX18/TBX15 Antibody (PACO01591)

SKU:
PACO01591
Product Type:
Antibody
Reactivity:
Human
Mouse
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
WB
IHC
IF
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
$323
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Description

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Antibody Name:TBX18/TBX15 Antibody
Antibody SKU:PACO01591
Size:50ug
Host Species:Rabbit
Tested Applications:ELISA, WB, IHC, IF
Recommended Dilutions:WB:1:500-1:2000, IHC:1:100-1:300, IF:1:200-1:1000
Species Reactivity:Human, Mouse
Immunogen:synthesized peptide derived from the Internal region of human TBX15/18.
Form:Liquid
Storage Buffer:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Synonyms:TBX18; T-box transcription factor TBX18; T-box protein 18; TBX15; TBX14; T-box transcription factor TBX15; T-box protein 15; T-box transcription factor TBX14; T-box protein 14
UniProt Protein Function:TBX18: Probable transcriptional regulator involved in developmental processes.
UniProt Protein Details:

Protein type:Transcription factor; DNA-binding

Chromosomal Location of Human Ortholog: 6q14-q15

Cellular Component: nucleus

Molecular Function:protein binding; protein heterodimerization activity; protein homodimerization activity; transcription factor activity

Biological Process: anterior/posterior axis specification; morphogenesis of embryonic epithelium; negative regulation of transcription from RNA polymerase II promoter; positive regulation of cell-cell adhesion; positive regulation of epithelial cell proliferation; sensory perception of sound; smooth muscle cell differentiation; somitogenesis; transcription, DNA-dependent

Disease: Huntington Disease

NCBI Summary:This genes codes for a member of an evolutionarily conserved family of transcription factors that plays a crucial role in embryonic development. The family is characterized by the presence of the DNA-binding T-box domain and is divided into five sub-families based on sequence conservation in this domain. The encoded protein belongs to the vertebrate specific Tbx1 sub-family. The protein acts as a transcriptional repressor by antagonizing transcriptional activators in the T-box family. The protein forms homo- or heterodimers with other transcription factors of the T-box family or other transcription factors. [provided by RefSeq, Nov 2012]
UniProt Code:O95935
NCBI GenInfo Identifier:122937456
NCBI Gene ID:9096
NCBI Accession:NP_001073977.1
UniProt Secondary Accession:O95935,Q7Z6U4, Q9UJI6, A2RU13,
UniProt Related Accession:O95935
Molecular Weight:80.8 kDa
NCBI Full Name:T-box transcription factor TBX18
NCBI Synonym Full Names:T-box 18
NCBI Official Symbol:TBX18  
NCBI Protein Information:T-box transcription factor TBX18
UniProt Protein Name:T-box transcription factor TBX18
Protein Family:T-box transcription factor
UniProt Gene Name:TBX18  
UniProt Entry Name:TBX18_HUMAN

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