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Understanding PD-1 Blockade in B-Cell Lymphomas Understanding PD-1 Blockade in B-Cell Lymphomas Introduction The programmed cell death protein 1 (PD-1) and its ligand PD-L1 have emerged as pivotal players in the landscape of cancer immunotherapy, particularly in B-cell lymphomas. This article explores the role of PD-1 and PD-L1 in these malignancies, highlighting the potential of PD-1 blockade as a therapeutic strategy. We will review ongoing clinical trials and discuss the implications for patient treatment. Study Summary In recent years, the expression of PD-1 and PD-L1 has been extensively studied in B-cell lymph …