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Immunopeptidomics: Mapping the Hidden Landscape of the Cancer Immunome
Imagine a high-stakes game of hide-and-seek where the seeker is your immune system and the hider is a master of disguise: cancer. For decades, we believed the 'wanted' posters for tumor cells were limited to a few well-known mutations. However, a revolutionary field called immunopeptidomics is revealing that the surface of a cancer cell is actually covered in thousands of hidden messages, waiting to be decoded by the next generation of precision medicine.
Introduction
The human immune system relies on a sophisticated surveillance mechanism to distinguish 'self' from 'non-self.' At the heart of this process are Major Histocompatibility Complex (MHC) molecules, which act as cellular display c
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24th Mar 2026