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A New Dawn in Lupus Treatment: The Promise of Topical RNA Therapeutics Systemic Lupus Erythematosus (SLE) is a debilitating autoimmune disease that has long puzzled researchers and clinicians. However, a groundbreaking development from the Hudson Institute of Medical Research in Melbourne offers a glimmer of hope. Researchers have developed a novel RNA-based topical cream that has shown remarkable potential in a world-first clinical trial, a finding that could revolutionize how we approach not just lupus, but a range of autoimmune disorders. This innovative approach, which leverages single-cell RNA sequencing to understand the disease at a molecular level, is paving the way for a new era of …

Breakthrough Discovery: Epstein-Barr Virus Identified as Primary Trigger for Lupus A groundbreaking study published in November 2025 has provided the most definitive evidence to date that the common Epstein-Barr virus (EBV) is a primary trigger for systemic lupus erythematosus (SLE), a complex and debilitating autoimmune disease. The research, led by a team at Stanford University, uncovers the precise cellular mechanisms by which this nearly ubiquitous virus can cause the immune system to turn against the body's own tissues, a finding that could revolutionize the diagnosis and treatment of lupus and other autoimmune disorders. For decades, scientists have suspected a link between EBV and lu …