Blog
Beyond Burnout: How T Cell Exhaustion Hijacks Cancer Immunity and What We Can Do About It
Imagine a highly trained soldier, elite and effective, sent to the front lines of a relentless war. Day after day, they fight without rest, their supplies dwindle, and the enemy never stops coming. Eventually, even the best soldier burns out. They stop fighting, not from a lack of will, but from sheer exhaustion. This is precisely what happens to our most powerful immune cells—T cells—in the fight against cancer. They become 'exhausted,' a state of cellular burnout that allows tumors to thrive. But what if we could wake them up? Recent breakthroughs are revealing not only how this exhaustion happens, but also how we can reverse it, offering new hope for patients who don't respond to current
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4th Dec 2025