Anti-FIBP Antibody (CAB13572)

Antibody Name:	Anti-FIBP Antibody
Antibody SKU:	CAB13572
Antibody Size:	20uL, 50uL, 100uL
Application:	WB IHC
Reactivity:	Human, Mouse
Host Species:	Rabbit
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-364 of human FIBP (NP_004205.2).

Application:	WB IHC
Recommended Dilution:	WB 1:500 - 1:2000 IHC 1:50 - 1:200
Reactivity:	Human, Mouse
Positive Samples:	BxPC-3, Mouse skeletal muscle

Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-364 of human FIBP (NP_004205.2).
Purification Method:	Affinity purification
Storage Buffer:	Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:	IgG
Sequence:	MTSE LDIF VGNT TLID EDVY RLWL DGYS VTDA VALR VRSG ILEQ TGAT AAVL QSDT MDHY RTFH MLER LLHA PPKL LHQL IFQI PPSR QALL IERY YAFD EAFV REVL GKKL SKGT KKDL DDIS TKTG ITLK SCRR QFDN FKRV FKVV EEMR GSLV DNIQ QHFL LSDR LARD YAAI VFFA NNRF ETGK KKLQ YLSF GDFA FCAE LMIQ NWTL GAVD SQMD DMDM DLDK EFLQ DLKE LKVL VADK DLLD LHKS LVCT ALRG KLGV FSEM EANF KNLS RGLV NVAA KLTH NKDV RDLF VDLV EKFV EPCR SDHW PLSD VRFF LNQY SASV HSLD GFRH QALW DRYM GTLR GCLL RLYH D
Gene ID:	9158
Uniprot:	O43427
Cellular Location:	Endomembrane system, Nucleus, Peripheral membrane protein
Calculated MW:	41kDa
Observed MW:	42kDa

Synonyms:

FIBP, FGFIBP, FIBP-1, TROFAS

Background:

Acidic fibroblast growth factor is mitogenic for a variety of different cell types and acts by stimulating mitogenesis or inducing morphological changes and differentiation. The FIBP protein is an intracellular protein that binds selectively to acidic fibroblast growth factor (aFGF). It is postulated that FIBP may be involved in the mitogenic action of aFGF. Two transcript variants encoding different isoforms have been found for this gene.

UniProt Protein Function:	FIBP: May be involved in mitogenic function of FGF1. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:	Chromosomal Location of Human Ortholog: 11q13.1 Cellular Component: nucleoplasm; membrane; mitochondrion; endomembrane system; nucleus Molecular Function:fibroblast growth factor binding Biological Process: fibroblast growth factor receptor signaling pathway
NCBI Summary:	Acidic fibroblast growth factor is mitogenic for a variety of different cell types and acts by stimulating mitogenesis or inducing morphological changes and differentiation. The FIBP protein is an intracellular protein that binds selectively to acidic fibroblast growth factor (aFGF). It is postulated that FIBP may be involved in the mitogenic action of aFGF. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Code:	O43427
NCBI GenInfo Identifier:	13431517
NCBI Gene ID:	9158
NCBI Accession:	O43427.3
UniProt Secondary Accession:	O43427,Q27Q85, Q6IBQ3, Q9HD65, A8K0J7,
UniProt Related Accession:	O43427
Molecular Weight:	364
NCBI Full Name:	Acidic fibroblast growth factor intracellular-binding protein
NCBI Synonym Full Names:	fibroblast growth factor (acidic) intracellular binding protein
NCBI Official Symbol:	FIBP
NCBI Official Synonym Symbols:	FGFIBP; FIBP-1
NCBI Protein Information:	acidic fibroblast growth factor intracellular-binding protein; aFGF intracellular-binding protein; FGF-1 intracellular-binding protein
UniProt Protein Name:	Acidic fibroblast growth factor intracellular-binding protein
UniProt Synonym Protein Names:	FGF-1 intracellular-binding protein
Protein Family:	Acidic fibroblast growth factor intracellular-binding protein
UniProt Gene Name:	FIBP
UniProt Entry Name:	FIBP_HUMAN

	Western blot analysis of extracts of various cell lines, using FIBP antibody (CAB13572) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.
	Immunohistochemistry of paraffin-embedded mouse heart using FIBP antibody (CAB13572) at dilution of 1:100 (40x lens).

Antibodies

Anti-FIBP Antibody (CAB6436)

Anti-FIBP Antibody (CAB19908)[KO Validated]

Secondary Antibody

Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)