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FITC Anti-Mouse CD45R/B220 Antibody [RA3.3A 1/6.1] (AGEL2214)

Datasheet MSDS
SKU AGEL2214
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FCM
Reactivity Mouse
Host Species Rat
Isotype Rat IgM, κ
Clone RA3.3A 1/6.1
Conjugation FITC
$25 - $79

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Description

system_update_altDatasheetsystem_update_altMSDS

FITC Anti-Mouse CD45R/B220 Antibody [RA3.3A 1/6.1]

The FITC Anti-Mouse CD45R/B220 Antibody (RA3-6B2) from Assaygenie is a high-quality research tool designed for the study of immune cells expressing CD45R/B220 in mice. With its specificity and sensitivity, this antibody is ideal for flow cytometry and immunofluorescence applications, enabling the identification and analysis of B cells and subsets within the immune system.

The RA3-6B2 antibody is derived from hybridoma cells, ensuring consistent performance and reliable results in experiments related to immunology, cancer research, and infectious diseases. Invest in this antibody to elevate your research and gain valuable insights into the immune response mechanisms in mouse models.

Product Title:FITC Anti-Mouse CD45R/B220 Antibody [RA3.3A 1/6.1]
SKU:AGEL2214
Size:25µg, 100µg
Clone No:RA3.3A 1/6.1
Synonyms:B220;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgM, κ
Isotype Control:FITC Rat IgM, κ Isotype Control[RTK2118]
Form:Liquid
Conjugation:FITC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Gene ID:19264,5788
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD45R, also known as B220, is an isoform of CD45. It is a member of the protein tyrosine phosphatase (PTP) family with a molecular weight of approximately 180-240 kD. CD45R is expressed on B cells (at all developmental stages from pro-B cells through mature B cells), activated B cells, and subsets of T and NK cells. CD45R (B220) is also expressed on a subset of abnormal T cells involved in the pathogenesis of systemic autoimmunity in MRL-Faslpr and MRL-Fasgld mice. It plays a critical role in TCR and BCR signaling. The primary ligands for CD45 are galectin-1, CD2, CD3, and CD4. CD45R is commonly used as a pan-B cell marker; however, CD19 may be more appropriate for B cell specificity.

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