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[KO Validated] HK2 Rabbit Polyclonal Antibody (CAB0994)

SKU:
CAB0994
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Metabolism
  • KO Validated Antibodies 1 Anti-HK2 Antibody CAB0994KO Validated
  • KO Validated Antibodies 1 Anti-HK2 Antibody CAB0994KO Validated
  • KO Validated Antibodies 1 Anti-HK2 Antibody CAB0994KO Validated
  • KO Validated Antibodies 1 Anti-HK2 Antibody CAB0994KO Validated
  • KO Validated Antibodies 1 Anti-HK2 Antibody CAB0994KO Validated
$167 - $503
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:[KO Validated] HK2 Rabbit Polyclonal Antibody
SKU:CAB0994
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human Hexokinase II (NP_000180.2).
Sequence:MIAS HLLA YFFT ELNH DQVQ KVDQ YLYH MRLS DETL LEIS KRFR KEME KGLG ATTH PTAA VKML PTFV RSTP DGTE HGEF LALD LGGT NFRV LWVK VTDN GLQK VEME NQIY AIPE DIMR
Tested Applications:WB IHC-P IF/ICC ELISA
Recommended Dilution:WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200
Synonyms:HKII; HXK2; Hexokinase II
Positive Sample:RD,Mouse skeletal muscle
Conjugate:Unconjugated
Cellular Localization:Mitochondrion outer membrane.
Calculated MW:102kDa
Observed MW:102kDa

Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.

Purification Method:Affinity purification
Gene ID:3099
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates, using Hexokinase II Rabbit pAb (CAB0994) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.

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