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Human 8-oxoGuanine DNA Glycosylase / OGG1 ELISA Kit

SKU:
HUFI01316
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
O15527
Sensitivity:
0.094ng/ml
Range:
0.156-10ng/ml
ELISA Type:
Sandwich ELISA, Double Antibody
Synonyms:
OGG1, N-glycosylase, DNA lyase, 8-hydroxyguanine DNA glycosylase, 8-oxoguanine DNA glycosylase, AP lyase, DNA-apurinic or apyrimidinic site lyase, HOGG1, MMH, MUTMOGH1HMMH
Reactivity:
Human
€599
Frequently bought together:

Description

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Human 8-oxoGuanine DNA Glycosylase / OGG1 ELISA Kit

8-oxoGuanineDNAGlycosylase/OGG1 removes 8-oxoguanine, a mutagenic base byproduct that occurs when cells are exposed to reactive oxygen. 8-oxoGuanineDNAGlycosylase/OGG1 contains a mitochondrial targeting signal for mitochondrial localization and lyase activity to cleave chains. Renal Cell Carcinoma and Nonpapillary Asbestosis are all diseases linked to OGG1. Depurination and cleavage of the damaged pyrimidine are two 8-oxoGuanineDNAGlycosylase/OGG1 related pathways.