The Mouse CD16/32 Monoclonal Antibody (AF647 Conjugated 2.4G2, AGEL0586) is a specialized antibody designed for research involving mouse CD16/32, key cell surface molecules that play a crucial role in immune responses. This monoclonal antibody, conjugated with AF647 for detection purposes, is highly specific and ideal for various immunological studies.CD16/32, also known as FcγRIII/FcγII receptor, is involved in antibody-dependent cell-mediated cytotoxicity (ADCC) and phagocytosis. This antibody binds specifically to CD16/32, facilitating the detection and analysis of these important molecules in different cell types and experimental settings.
Researchers in immunology, cancer biology, and infectious diseases can benefit from the use of this antibody for their studies.Given the significance of CD16/32 in immune cell activation and function, understanding its role can provide insights into immune responses, autoimmune diseases, and therapeutic antibody treatments. This antibody offers a valuable tool for investigating the function and regulation of CD16/32, contributing to advancements in immunotherapy and disease research.
CD16a/b;CD32;CD32A/B;Fc fragment of IgG low affinity IIa/b receptor;Fc fragment of IgG low affinity IIIa/b receptor;Fc fragment of IgG low affinity IIIb receptor;Fc gamma receptor III A/B;FCG2A;FcGR;FCGR2A/BFCGR3;FCGR3A/B;Fc gamma RIIa/b ;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2b, κ
Isotype Control:
Genie Fluor 647 Rat IgG2b, κ Isotype Control[LTF-2]
Form:
Liquid
Conjugation:
Genie Fluor647
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P08508 P08101
Gene ID:
14130,14131
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD16 is low affinity IgG Fc receptor III (FcR III) and CD32 is FcR II. CD16/CD32 are expressed on B cells, monocytes/macrophages, NK cells, granulocytes, mast cells, and dendritic cells. The Fc receptors bind antibody-antigen immune complexes and mediate adaptive immune responses.
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