Biotin Anti-Mouse CD161/NK1.1 Antibody [PK136] (AGEL0011)
- SKU:
- AGEL0011
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Mouse
- Host Species:
- Mouse
- Isotype:
- IgG2a
- Clone:
- PK136
- Conjugation:
- Biotin
- Applications:
- FC
Frequently bought together:
Description
Product Title: | Biotin Anti-Mouse CD161/NK1.1 Antibody [PK136] |
SKU: | AGEL0011 |
Size: | 25µg, 100µg |
Clone No: | PK136 |
Synonyms: | Killer cell lectin-like receptor subfamily B member 1C;Klrb1c;CD161 antigen-like family member C;Ly-55c;CD161/NK1.1;NKR-P1.9;NKR-P1C;NKR-P1 40;CD161c; |
Host Species: | Mouse |
Reactivity: | Mouse |
Application: | FCM |
Isotype: | Mouse IgG2a, κ |
Isotype Control: | Biotin Mouse IgG2a, κ Isotype Control[C1.18.4] |
Form: | Liquid |
Conjugation: | Biotin |
Recommended Use: | Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. |
Swissprot: | P27814 P27812 Q99JB4 |
Gene ID: | 17059 |
Storage Buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
Stability & Storage: | Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase. |
Background: | NK-1.1 surface antigen, also known as CD161b/CD161c and Ly-55, is encoded by the NKR-P1B/NKR-P1C gene. It is expressed on NK cells and NK-T cells in some mouse strains, including C57BL/6, FVB/N, and NZB, but not AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129. Expression of NKR-P1C antigen has been correlated with lysis of tumor cells in vitro and rejection of bone marrow allografts in vivo. NK-1.1 has also been shown to play a role in NK cell activation, IFN-γ production, and cytotoxic granule release. NK-1.1 and DX5 are commonly used as mouse NK cell markers. |