UniProt Protein Function: | NPAS4: Acts as a transcriptional activator in the presence of ARNT. Can activate the CME (CNS midline enhancer) element and the expression of the drebrin gene.Protein type: DNA-bindingChromosomal Location of Human Ortholog: 11q13Cellular Component: transcription factor complex; nucleusMolecular Function: signal transducer activity; protein heterodimerization activityBiological Process: transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; signal transduction |
UniProt Protein Details: | |
NCBI Summary: | NXF is a member of the basic helix-loop-helix-PER (MIM 602260)-ARNT (MIM 126110)-SIM (see SIM2; MIM 600892) (bHLH-PAS) class of transcriptional regulators, which are involved in a wide range of physiologic and developmental events (Ooe et al., 2004 [PubMed 14701734]).[supplied by OMIM, Mar 2008] |
UniProt Code: | Q8IUM7 |
NCBI GenInfo Identifier: | 194097477 |
NCBI Gene ID: | 266743 |
NCBI Accession: | NP_849195.2 |
UniProt Secondary Accession: | Q8IUM7,Q8N8S5, Q8N9Q9, B7ZL81 |
UniProt Related Accession: | Q8IUM7 |
Molecular Weight: | |
NCBI Full Name: | neuronal PAS domain-containing protein 4 |
NCBI Synonym Full Names: | neuronal PAS domain protein 4 |
NCBI Official Symbol: | NPAS4Â Â |
NCBI Official Synonym Symbols: | NXF; Le-PAS; PASD10; bHLHe79Â Â |
NCBI Protein Information: | neuronal PAS domain-containing protein 4 |
UniProt Protein Name: | Neuronal PAS domain-containing protein 4 |
UniProt Synonym Protein Names: | Class E basic helix-loop-helix protein 79; bHLHe79; HLH-PAS transcription factor NXF; PAS domain-containing protein 10 |
Protein Family: | Neuronal PAS domain-containing protein |
UniProt Gene Name: | NPAS4Â Â |
UniProt Entry Name: | NPAS4_HUMAN |