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PerCP/Cyanine5.5 Anti-Rat CD45 Antibody [OX-1] (AGEL2453)

Datasheet MSDS
SKU AGEL2453
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FCM
Reactivity Rat
Host Species Mouse
Isotype Mouse IgG1, κ
Clone OX-1
Conjugation PerCP/Cyanine5.5
€125 - €325

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Description

system_update_altDatasheetsystem_update_altMSDS

PerCP/Cyanine5.5 Anti-Rat CD45 Antibody [OX-1]

The PerCP-Cyanine5.5 Anti-Rat CD45 Antibody (OX-1) is a valuable tool for immunology research, specifically designed to target the CD45 antigen in rat samples. CD45 is a cell surface glycoprotein that plays a crucial role in immune cell signaling and activation, making it a key marker in immunological studies.This antibody is optimized for flow cytometry applications, offering high sensitivity and specificity in detecting CD45 expression in rat immune cells. Its PerCP-Cyanine5.5 conjugate provides bright and stable fluorescent signal, allowing for accurate and reliable quantification of CD45-positive cell populations.

By targeting CD45, researchers can investigate immune cell subpopulations, monitor immune responses, and study diseases such as autoimmune disorders, inflammatory conditions, and cancer. The PerCP-Cyanine5.5 Anti-Rat CD45 Antibody (OX-1) is a valuable tool for unraveling the complexities of immune function and exploring potential therapeutic strategies in various disease settings.

Product Title:PerCP/Cyanine5.5 Anti-Rat CD45 Antibody [OX-1]
SKU:AGEL2453
Size:25µg, 100µg
Clone No:OX-1
Synonyms:Receptor-type tyrosine-protein phosphatase C;Leukocyte common antigen; LCA; T200; Ly-5;Ptprc;
Host Species:Mouse
Reactivity:Rat
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:PerCP/Cyanine5.5 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:PerCP/Cyanine 5.5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P04157
Gene ID:19265
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD45 is a 180-220 kD protein also known as leukocyte common antigen (LCA). It is a protein tyrosine phosphatase with multiple isoforms differing as a result of alternative splicing of the extracellular domain and glycosylation. CD45 is expressed on all hematopoietic cells except erythrocytes and platelets; isoform expression depends on cell type, activation state, and cell maturation. CD45 functions in signal transduction through T and B cell antigen receptors. CD45 has been shown to interact with various proteins including galectin-1, CD2, CD3, and CD4. The OX-1 antibody has been shown to partially inhibit NK cell-mediated lysis of syngeneic tumor cells in vitro.

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