The PLCB2 Antibody (CAB8141) is a high-quality antibody developed for reliable detection and analysis of target proteins. The antibody is produced using rabbits and has been shown to exhibit high reactivity with human samples. Validated for use in Western blot applications, this antibody binds specifically to the PLCB2 protein, allowing for accurate detection and analysis in various cell types.PLCB2 is an essential enzyme involved in the regulation of cellular signaling, particularly in processes related to immune responses and cell growth. Dysregulation of PLCB2 has been implicated in various diseases, including cancer, autoimmune disorders, and neurological conditions.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
PLCB2 Antibody
SKU:
CAB8141
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
The protein encoded by this gene is a phosphodiesterase that catalyzes the hydrolysis of phosphatidylinositol 4,5-bisphosphate to the second messengers inositol 1,4,5-trisphosphate (IP3) and diacylglycerol. The encoded protein is activated by G proteins and has been shown to be involved in the type 2 taste receptor signal transduction pathway. In addition, nuclear factor kappa B can regulate the transcription of this gene, whose protein product is also an important regulator of platelet responses.
Purification Method
Affinity purification
Gene ID
5330
RRID
AB_2771703
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of lysates from Rat lung, using PLCB2 Rabbit pAb (CAB8141) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 180s.
Western blot analysis of lysates from HEL cells, using PLCB2 Rabbit pAb (CAB8141) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (AbGn00021). Exposure time: 90s.
