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RARβ Rabbit Monoclonal Antibody (CAB4535)

SKU:
CAB4535
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Epigenetics and Nuclear Signaling
$167 - $503
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:RARβ Rabbit Monoclonal Antibody
SKU:CAB4535
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 350-455 of human RARβ (NP_000956.2).
Sequence:KLQE PLLE ALKI YIRK RRPS KPHM FPKI LMKI TDLR SISA KGAE RVIT LKME IPGS MPPL IQEM LENS EGHE PLTP SSSG NTAE HSPS ISPS SVEN SGVS QSPL VQ
Tested Applications:WB IF/ICC ELISA
Recommended Dilution:WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200
Synonyms:HAP; RRB2; NR1B2; MCOPS12; RARbeta; RARbeta1; RARβ
Positive Sample:HeLa, Hep G2, HUVEC
Conjugate:Unconjugated
Cellular Localization:Cytoplasm, Nucleus
Calculated MW:50kDa
Observed MW:55kDa

This gene encodes retinoic acid receptor beta, a member of the thyroid-steroid hormone receptor superfamily of nuclear transcriptional regulators. This receptor localizes to the cytoplasm and to subnuclear compartments. It binds retinoic acid, the biologically active form of vitamin A which mediates cellular signalling in embryonic morphogenesis, cell growth and differentiation. It is thought that this protein limits growth of many cell types by regulating gene expression. The gene was first identified in a hepatocellular carcinoma where it flanks a hepatitis B virus integration site. Alternate promoter usage and differential splicing result in multiple transcript variants.

Purification Method:Affinity purification
Gene ID:5915
Clone Number:ARC1024
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using RARβ Rabbit mAb (CAB4535) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.

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