Shigella Infection (Shigellosis) Antibodies, Proteins & ELISA Kits

Shigella Antibodies, Proteins & ELISA Kits | Assay Genie

Infectious Disease · Shigella species

Shigella antibodies, proteins & ELISA kits

Shigellosis is a highly infectious cause of bacillary dysentery caused by Shigella species; S. dysenteriae produces Shiga toxin, and the O-antigen of LPS defines serotypes.

ShigellaShiga toxin / LPSDysentery

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Shigella

Gram-negative

Shiga toxin

Key virulence factor

Faecal-oral

Low dose

Dysentery

Bloody diarrhoea

Overview

What is Shigella?

Shigellosis is a highly infectious cause of bacillary dysentery caused by Shigella species; S. dysenteriae produces Shiga toxin, and the O-antigen of LPS defines serotypes.

Transmission is faecal-oral and requires only a low infectious dose. Antibody and antigen assays support diagnosis, serotyping research and vaccine development.

Transmission & symptoms

Shigella causes bacillary dysentery and is highly transmissible by the faecal-oral route, needing only a very low infectious dose. It invades the colonic epithelium, causing bloody, mucoid diarrhoea; S. dysenteriae type 1 also produces Shiga toxin.

Diagnosis & serology

Diagnosis uses stool culture and PCR; serotyping is based on the O-antigen of lipopolysaccharide. Antibody and antigen assays support surveillance and vaccine research.

Research applications

Research tools cover host innate responses to invasion (IL-8, caspase-1/inflammasome, NOD1, defensins) and O-antigen/Shiga-toxin immunity relevant to vaccine development.

Products

Shigella antibodies, proteins & ELISA kits

Validated, in-stock research tools for Shigella — every link checked and live.

Related research targets

Host receptors, biomarkers and immune targets relevant to Shigella — antibodies, ELISA kits and In Vivo antibodies from our current catalogue.

Anti-Human IL-8 Capture AntibodyIL-8 · AntibodyView →Anti-Human IL-8 Detection AntibodyIL-8 · AntibodyView →Anti-Human IL-8 Capture AntibodyIL-8 · AntibodyView →Anti-Caspase-10 AntibodyCaspase-1 · AntibodyView →Anti-Caspase-12 AntibodyCaspase-1 · AntibodyView →Anti-Caspase-1 AntibodyCaspase-1 · AntibodyView →Human NOD1 (Nucleotide-binding oligomerization domain-containing protein 1) ELISA KitNOD1 · ELISA kitView →Anti-Human Alpha Defensin-5 [8C8] In Vivo Antibody - Low EndotoxinDefensin · In Vivo antibodyView →Anti-Human BD-1/beta-Defensin 1 Capture AntibodyDefensin · AntibodyView →Anti-Human BD-1/beta-Defensin 1 Detection AntibodyDefensin · AntibodyView →

FAQs

Shigella — frequently asked questions

How is shigellosis diagnosed?

By stool culture and PCR, with serotyping based on the lipopolysaccharide O-antigen; serology supports epidemiological research.

Why is Shigella so infectious?

It survives stomach acid well and needs only a very low infectious dose, so it spreads readily person-to-person and through contaminated food/water.

What host responses does Shigella trigger?

Epithelial invasion activates inflammasome/caspase-1, IL-8-driven neutrophil recruitment and NOD1 signalling, causing the intense colonic inflammation of dysentery.

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